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孙伟正,王祥麒,袁斌华,孙风,马军,陈立君,展昭民,孙劲晖.补髓生血胶囊治疗慢性再生障碍性贫血的临床观察[J].,1997,(8):467-469
补髓生血胶囊治疗慢性再生障碍性贫血的临床观察
Clinical Study on Treatment of Chronic Aplastic Anemia with Busui Shengxue Capsule
DOI:
中文关键词
:
慢性再生障碍性贫血
补髓生血胶囊
造血干/祖细胞
白细胞介素
英文关键词
:
chronic aplastic anemia
Busui Shengxue Capsule
hematopoietic stem cell
progenitor cell
interleukin
基金项目
:
黑龙江省自然科学基金
Author Name
Affiliation
孙伟正
王祥麒
袁斌华
孙风
马军
陈立君
展昭民
孙劲晖
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中文摘要
:
探讨补髓生血胶囊治疗慢性再生障碍性贫血的理论依据。方法:采用造血细胞培养和流式细胞仪技术,对口服补髓生血胶囊的35例患者治疗4个月前后的骨髓单个核细胞进行对比观察。结果:(1)本品具有恢复造血干/祖细胞膜IL-3,IL-6,IL-11受体的作用;(2)补髓生血胶囊的疗效优于西药(P<0.05);(3)治疗组中肾阳虚与肾阴虚型治疗前的造血干/祖细胞在IL-3、IL-6、IL-11刺激下,其细胞集落产生率和CD ̄+_(34)细胞率有显著性差异(P<0.05),治疗后两型相比也有显著性差异(P<0.05)。结论:本品通过患者体内调控因子使造血干细胞膜受体改变而起治疗作用。
英文摘要
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