| 谢雁鸣,张方直,周文泉,高普,傅仁杰,赵天予,李承军.补骨生髓胶囊治疗肾阳虚证原发性骨质疏松症的临床研究[J].,1997,(9):526-530 |
| 补骨生髓胶囊治疗肾阳虚证原发性骨质疏松症的临床研究 |
| Clinical Study of Bugu Shengsui Capsule in Treating Primary Osteoporosis with Kidney-Yang Deficiency Syndrome |
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| DOI： |
| 中文关键词: 补肾法 补骨生髓胶囊 原发性骨质疏松症 |
| 英文关键词:Tonification of Kidney Bugu Shengsui Capsule primary osteoporosis |
| 基金项目:国家中医药管理局青年基金 |
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| 中文摘要: |
| 目的：评价补肾法治疗肾阳虚证的原发性骨质疏松症的临床效果。方法：采用补骨生髓胶囊治疗８０例该病患者，并用美国Ｌｕｎａｒ公司ＤＰＸ－Ｌ型双能Ｘ线有关指标仪及放射免疫法等检测治疗前后有关指标。结果：补骨生髓胶囊临床显效率及总有效率分别为４６％和８２％，其疗效明显高于对照组（维生素Ｄ加钙剂）。经双能Ｘ线骨密度（ＤＥＸＡ）证实，补骨生髓胶囊能明显提高原发性骨质疏松症患者的骨密度。该药还能提高降钙素、促黄体生成素及血钙水平和降低甲状旁腺素水平。结论：补肾法治疗原发性骨质疏松的作用是通过提高患者的骨密度，抑制骨吸收，减少骨量丢失等环节实现的。 |
| 英文摘要: |
| To assess the effect of Bugu Shengsui capsule (BGSSC) in treating primary osteoporosis. Meththe:Using double energy X-ray bone densimeter and radioimmunoassay (RIA), the effect of BGSSC in treating primaryosteoporosis (OP) with Kidney-Yang Deficiency syndrome. Results: The clinical markedly effective and total effective rates of BGSSC were 46% and 82%, respectively. The rate of TCM group is significantly higher than that ofthe control group (Vitamin D plus calcium). BGSSC could improve bone mineral density by the verification of double energy X-ray bone dansity(DEXA). It could also increase the level of serum calcitonin, luteinizing home andcalcium, decrease the activity of parathyroid hormone. Conclusions: The effects of BGSSC on primary OP includedincreasing patient’s bone mineral density, depressing bone resorption and decreaSing bone loss. |
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