| 徐东,许仁和.补肾防喘片与必可酮防治季节性哮喘发作的研究[J].,1997,(12):721-723 |
| 补肾防喘片与必可酮防治季节性哮喘发作的研究 |
| Prevention and Treatment of Seasonal Asthmatic Patients by Combined Invigorating Kidney for Preventing Asthma Tablets and Beclomethasone Dipropinate |
| |
| DOI： |
| 中文关键词: 哮喘 嗜酸细胞 T淋巴细胞 嗜酸细胞阳离子蛋白 补肾防喘片 |
| 英文关键词:asthma eosinophils T lymphocytes serum eosinophil cationic protein Invigorating Kidney for Preventing Asthma Tablets |
| 基金项目: |
|
| Hits: 1455 |
| Download times: 1060 |
| 中文摘要: |
| 目的：为探讨补肾防喘片、必可酮防治季节性哮喘发作的效果。方法：选择了５７例轻、中度患者并随机分成两组，治疗组３２例服补肾防喘片及吸入必可酮；对照组２５倒吸入必可酮。治疗３个月后复查并连续观察０．５年。治疗前后分别测定嗜酸细胞计数、可溶性白介素－２受体（ＳＩＬ－２Ｒ）、嗜酸细胞阳离子蛋白（ＥＣＰ）及做肺功能、气道反应性。结果：治疗组疗效明显优于对照组。治疗组ＥＣＰ下降及１秒钟用力呼气量（ＦＥＶ１）的增加也较对照组明显。结论：两药合用在防治哮喘发作上明显优于单纯吸入必可酮组，这可能与影响Ｔ淋巴细胞及嗜酸细胞的功能有关。 |
| 英文摘要: |
| Objective: To evaluate the efficacy of combined invigorating Kidney for Preventing Asthma (IKPA) tablets and beclomethasone dipropinate (BDP). Methods: Fifty-seven seasonal asthmatic patients were studied. They were randomly assigned to either of the two groups: the treated group (n= 32) treated with the IKPA tablets and inhalated BDP, the control group (n= 25) inhalated BDP singly. Measurements of serum eosinophil cationic protein (ECP), soluble IL-2 receptor (SIL-2), total eosinophil counts, spirometry and methacholine challenge were performed before and after treatment. Results: After 3 months’ treatment and 6 months’ observation the authors observed a significant improvement in both groups. The treated group had better clinical efficacy and the ECP level had reduced significantly, FEVI increased greatly than the control group. Conclusions: The two drugs influenced the function of eosinophils and and T lymphocytes and this might contribute to the efficacy. |
| View Full Text View/Add Comment Download reader |
