| 王硕仁,赵明镜,吕希滢,赵悦茹,徐西.冠心病心气虚证与左心室功能及心肌缺血相关性的临床研究[J].,1998,(8):457-460 |
| 冠心病心气虚证与左心室功能及心肌缺血相关性的临床研究 |
| Clinical Study on Relationship among Heart-Qi Deficiency, Left Ventricular Function and Myocardial Ischemia in Patients with Coronary Heart Disease |
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| DOI： |
| 中文关键词: 冠心病 心气虚证 左心室功能 心肌缺血 党参 |
| 英文关键词:coronary heart disease Heart Qi Deficiency left ventricular function myocardial ischemia Radix Codonopsitis Pilosulae |
| 基金项目:国家自然科学基金资助项目!(No .39470 881) |
| Author Name | Affiliation | | 王硕仁 | Wang Shuoren, Zhao Mingjing, Lu Xiying, et al Dongzhimen Hospital, Beijing University of TCM, Beijing (100700 | | 赵明镜 | Wang Shuoren, Zhao Mingjing, Lu Xiying, et al Dongzhimen Hospital, Beijing University of TCM, Beijing (100700 | | 吕希滢 | Wang Shuoren, Zhao Mingjing, Lu Xiying, et al Dongzhimen Hospital, Beijing University of TCM, Beijing (100700 | | 赵悦茹 | Wang Shuoren, Zhao Mingjing, Lu Xiying, et al Dongzhimen Hospital, Beijing University of TCM, Beijing (100700 | | 徐西 | Wang Shuoren, Zhao Mingjing, Lu Xiying, et al Dongzhimen Hospital, Beijing University of TCM, Beijing (100700 |
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| 中文摘要: |
| 目的 :研究冠心病心气虚证与左心室功能和心肌供血三者的相关性。方法 :以多普勒超声心动图、体表心电图等方法进行宏观辨证与微观辨证研究 ;应用党参与硝苯吡啶治疗稳定性心绞痛 ,进行药证结合研究。结果 :(1 )冠心病心气虚证与非心气虚证组比较 ,左室舒张和收缩功能部分检测指标有显著性差异 ;左室舒张功能评价对心气虚证诊断有高敏感性(87% ) ,左室收缩功能则有高特异性 (88% )。 (2 )党参可保护左室舒张和收缩功能 ,改善心肌缺血。结论 :心肌缺血和血瘀可造成心气虚证 ,补气治疗心气虚证又可反作用于血瘀证 ,使心肌缺血好转。其机制为改善心肌正性舒张和收缩功能 ,从而改善心肌血供的灌注阻力和压力 ,有利于心肌供血。 |
| 英文摘要: |
| Objective: To study the relationship among Heart Qi Deficiency (HQD), left ventricular function and myocardial ischemia in patients with coronary heart disease (CHD). Methods: Doppler echocardiogram, electrocardiogram were used to observe 103 patients of CHD clinically. Patients of stable angina pectoris treated with Radix Codonopsitis Pilosulae (50 cases) or Nifedipine (20 cases) were observed as well. Results: Occurrence of left ventricular function insufficiency, both systolic and diastolic, was higher in CHD patients of HQD type as compared with that of non HQD type. The left ventricular diastolic function showed high susceptibility (87%) and the left venticular systolic function showed high specificity (88%) for HQD evaluation. Radix Codonopsitis Pilosulae could protect the left ventricular function and improve myocardial ischemia. Conclusions: Myocardial ischemia and blood stasis cause HQD, while the Chinese herbal medicine treatment on HQD could improve the blood stasis to alleviate myocardial ischemia effectively. The mechanism of which might be to enhance the positive diastolic and systolic function of cardiac muscles, reduce the resistance pressure and keep pressure of coronary perfusion so as to improve the blood supply of heart. |
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