| 裴静琛,杨天德,刘志强,常磊,孙若亮.TTS-ST93-1穴位贴剂防治运动病的观察[J].,1998,(8):464-467 |
| TTS-ST93-1穴位贴剂防治运动病的观察 |
| Study on Effect of Acupoint Sticker of TTS-ST93-1 in Treating Motion Sickness |
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| DOI： |
| 中文关键词: 运动病 抗运动病药 穴位贴剂 透皮治疗系统 |
| 英文关键词:motion sickness anti motion sickness agent acupoint sticker transdermal therapeutic system |
| 基金项目:国防科技跨行业基金资助!(No.93J9 0 13) |
| Author Name | Affiliation | | 裴静琛 | Pei Jingchen, Yang Tiande, Liu Zhiqiang, et al Institute of Space Medco Engineering, Beijing (100094 | | 杨天德 | Pei Jingchen, Yang Tiande, Liu Zhiqiang, et al Institute of Space Medco Engineering, Beijing (100094 | | 刘志强 | Pei Jingchen, Yang Tiande, Liu Zhiqiang, et al Institute of Space Medco Engineering, Beijing (100094 | | 常磊 | Pei Jingchen, Yang Tiande, Liu Zhiqiang, et al Institute of Space Medco Engineering, Beijing (100094 | | 孙若亮 | Pei Jingchen, Yang Tiande, Liu Zhiqiang, et al Institute of Space Medco Engineering, Beijing (100094 |
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| 中文摘要: |
| 目的 :确定合适的防治运动病的经络穴位 ,观察TTS -ST93 -1作为穴位贴剂的抗运动病作用。方法 :有近期晕车史的年青健康自愿者 1 63名 ,男性 ,乘卡车、装甲车 3h。采用随机分组、双盲实验方法。分为实验药物组 (TTS -ST93 -1贴剂膜片 ) ,阳性对照组 (TTS -Scop贴剂膜片 ) ,阴性对照组 (乳糖贴剂膜片 )。选择穴位 :内关、神阙、脉。实验药物组又分 :ST93 -1内关组 ,ST93 -1神阙组 ,ST93 -1脉组。按美国Graybiel制定的运动病症状数字评分法 ,评定被试者的晕车症状程度。结果 :ST93 -1贴剂的平均有效率为 95 9% ,与阴性对照组比较有显著性差异 (P <0 0 1 )。ST93 -1内关组的保护率为 45 5 % ,神阙组的保护率是81 4% ,脉组的保护率为 1 0 0 % ,平均保护率是 76 0 % ,与阳性对照组 (2 7 3 % )比较有显著性差异。ST93 -1贴剂引起的口干、嗜睡、困倦副作用的发生率与阴性对照组比较无显著性差异。被试者穴位上贴药 8h后 ,ST93 -1引起的皮肤红肿、痛、痒等过敏症状较轻。结论 :TTS -ST93 -1有效穴位贴剂是防治运动病的良好方法。 |
| 英文摘要: |
| Objective: To observe the effect of Transdermal Therapeutic System ST93-1 (TTS-ST93-1) by acupoint sticking in treating motion sickness (MS). Methods: One hundred and sixty three young volunteers with history of MS recently were subjected to a 3 hours journey by track and armored car, and divided randomly into tested, positive control and negative control groups, treated with TTS-ST93-1 plaster, TTS Scopolamine plaster and placebo (lactose plaster) respectively. The TTS-ST93-1 plaster was stuck on Neiguan (P6) or Shenque (CV8) or Qimai (TE18) point and the effect of treatment was observed by double blind method. Results: The mean effective rate of tested group was 95.9%, which was significantly different to that of the negative control group (P<0 01). In the tested group, the protection rate of plaster stuck on Shenque was 81.4%, on Neiguan was 45.5% and on Qimai was 100%, with an average of 76.0%, which was significantly different to that of the negative control group. The protection rate of TTS Scopolamine plaster was merely 27.3%. The side effects of TTS-ST93-1 plaster were mouth dryness, sleepiness and fatigue, as compared with the negative control group, the difference was insignificant. No allergic reaction of skin such as swelling, pain or itching was found in the tested group. Conclusion: Acupoint sticker of TTS-ST93-1 was an effective treatment for MS with less side effect and no allergic reaction of skin. |
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