| 陈安忠,赵社正,黄少檀,程莉,叶友联.支气管哮喘患者中医辨证分型与尿四种微量蛋白的关系[J].,1998,(9):537-539 |
| 支气管哮喘患者中医辨证分型与尿四种微量蛋白的关系 |
| Relationship between Syndrome Type in TCM and Four Trace Urinary Proteins in Patients with Bronchial Asthma |
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| DOI： |
| 中文关键词: 支气管哮喘 中医证型 尿白蛋白 尿免疫球蛋白G 尿β2微球蛋白 尿TammHorsfall蛋白 |
| 英文关键词:bronchial asthma Syndrome Type in TCM urinary albumin urinary immunoglobulin G urinary β 2 microglobulin urinary Tamm Horsfall protein |
| 基金项目: |
| Author Name | Affiliation | | 陈安忠 | Chen Anzhong, Zhao Shezheng, Huang Shaotan, et al PLA 458th Hospital, Guangzhou (510602 | | 赵社正 | Chen Anzhong, Zhao Shezheng, Huang Shaotan, et al PLA 458th Hospital, Guangzhou (510602 | | 黄少檀 | Chen Anzhong, Zhao Shezheng, Huang Shaotan, et al PLA 458th Hospital, Guangzhou (510602 | | 程莉 | Chen Anzhong, Zhao Shezheng, Huang Shaotan, et al PLA 458th Hospital, Guangzhou (510602 | | 叶友联 | Chen Anzhong, Zhao Shezheng, Huang Shaotan, et al PLA 458th Hospital, Guangzhou (510602 |
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| 中文摘要: |
| 目的 :探讨哮喘患者中医不同证型与尿中 4种微量蛋白的关系。方法 :用放射免疫法测定 2 17例哮喘患者尿中 4种微量蛋白 ,并与 6 6名健康人组对比。结果 :哮喘患者尿白蛋白 (UAlb)、尿免疫球蛋白G (UIgG)、尿 β2 微球蛋白 (Uβ2 m)、尿Tamm Horsfall蛋白(UTHP)呈不同程度增高 ,并按中医肺虚型、肺脾两虚型和肺肾两虚型顺序呈渐增趋势。并证实尿 4种微量蛋白测定对肾功能受损判断较血BUN、SCr灵敏。结论 :哮喘患者中医证型有其客观的物质基础 ,即其存在不同程度的肾小球滤过Alb、IgG功能受损 ,肾小管重吸收β2 m功能受损及肾小管合成排泌THP功能受损 |
| 英文摘要: |
| Objective: To explore the possible relationship between Syndrome Type in TCM and the 4 trace urinary proteins in patients with bronchial asthma. Methods: The 4 kinds of trace urinary proteins in 217 patients with asthma were measured by radioimmunoassay, and that in 66 normal subjects were compared. Results: The results showed that there were increments of urinary albumin, urinary IgG, urinary β 2 microglobulin and urinary Tamm Horsfall protein in patients with asthma; and the gradual increase tended to be accompanied by the continuous aggravation of patient’s condition on TCM Syndrome Type. Furthermore, these datas proved that the 4 trace urinary proteins might be the most sensitive indicators for detecting impaired renal functions than serum blood urea nitrogen and creatinine. Conclusions: There were the objective material foundations on TCM Syndrome Type in asthmatics, which consisted of renal glomerular dysfunctions to filter out albumin and IgG, renal tubular dysfunction to reabsorb β 2 microglobulin, and to synthesize and excrete Tamm Horsfall protein. |
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