| 夏代宇,曾奕新,廖志航.玉参降糖片治疗2型糖尿病临床与实验研究[J].,1999,(2):90-92 |
| 玉参降糖片治疗2型糖尿病临床与实验研究 |
| Clinical and Experimental Study of Yushen Jiangtang Tablet in Treating Non Insulin Dependent Diabetes Mellitus |
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| DOI： |
| 中文关键词: 玉参降糖片 2型糖尿病 临床观察 药效学试验 |
| 英文关键词:Yushen Jiangtang Tablet non insulin dependent diabetes mellitus clinical observation pharmacological study |
| 基金项目:四川省中医管理局科研基金 |
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| 中文摘要: |
| 目的：对玉参降糖片治疗２型糖尿病气阴两虚证患者的疗效及安全性作出评价。方法：临床验证玉参降糖片治疗２型糖尿病气阴两虚证患者１０１例，另随机设参芪降糖片对照组６０例，并进行毒理学和药效学试验。结果：治疗组总有效率为８７１３％，显效率为４４５５％，对照组分别为７０００％、１８３３％，两组比较，治疗组疗效优于对照组（Ｐ＜００１）。动物急性和长期毒性试验，未发现明显毒性作用。玉参降糖片可使四氧嘧啶引起的实验性糖尿病大鼠的血糖降低，并使实验性糖尿病大鼠的血清甘油三酯下降。结论：玉参降糖片治疗２型糖尿病气阴两虚证疗效确切，未发现明显毒副作用。 |
| 英文摘要: |
| Objective: To evaluate the therapeutic effect and safety of Yushen Jiangtang Tablet (YSJTT) in treating non insulin dependent diabetes mellitus (NIDDM) of Qi Yin Deficiency Syndrome (QYD). Methods: One hundred and one patients of NIDDM with QYD were treated with YSJTT and compared with 60 patients of the control group treated with Shenqi Jiangtang Tablet. The experimental study on pharmacologic effect and toxicity of YSJTT was also conducted. Results: The total effective rate of the YSJTT group was 87.12% and the markedly effective rate 44.55%, while those of the control group were 70.00% and 18.33% respectively, comparison between the two groups showed that the effect of the YSJTT group was superior to that of the control group, P<0 01. No acute or chronic toxic or side effect was found in animal experiment. Pharmacologic study showed that YSJTT had obvious effect in decreasing blood glucose and serum triglyceride levels in rats with alloxan induced diabetes. Conclusion: YSJTT is effective in treating NIDDM, and apparent toxic side effect of it was not found. |
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