| 章梅,张仲海,夏天,王宗仁,孙凯,徐重明,于文彬.四君子汤对脾虚患者血清可溶性细胞粘附分子-1水平和单核细胞功能的影响[J].,1999,(5):270-272 |
| 四君子汤对脾虚患者血清可溶性细胞粘附分子-1水平和单核细胞功能的影响 |
| Effect of Sijunzi Decoction on Serum Soluble Intercellular Adhesive Molecule 1, Interleukin 15 and Monocyte Antibody Dependent Cell Mediated Cytotoxicity in Patients of Spleen Deficiency |
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| DOI： |
| 中文关键词: 脾虚患者 四君子汤 可溶性细胞粘附分子-1 白细胞介素-15 抗体依赖性细胞介导的细胞毒反应 |
| 英文关键词:patient of Spleen Deficiency Sijunzi Decoction soluble intercellular adhesive molecule 1 interleukin 15 antibody dependent cell mediated cytotoxicity |
| 基金项目:国家自然科学基金 |
| Author Name | Affiliation | | 章梅 | Zhang Mei, Zhang Zhonghai, Xia Tian, et al Department of TCM, Xijing Hospital, the Fourth Military Medical University, Xi’an (710032 | | 张仲海 | Zhang Mei, Zhang Zhonghai, Xia Tian, et al Department of TCM, Xijing Hospital, the Fourth Military Medical University, Xi’an (710032 | | 夏天 | Zhang Mei, Zhang Zhonghai, Xia Tian, et al Department of TCM, Xijing Hospital, the Fourth Military Medical University, Xi’an (710032 | | 王宗仁 | Zhang Mei, Zhang Zhonghai, Xia Tian, et al Department of TCM, Xijing Hospital, the Fourth Military Medical University, Xi’an (710032 | | 孙凯 | Zhang Mei, Zhang Zhonghai, Xia Tian, et al Department of TCM, Xijing Hospital, the Fourth Military Medical University, Xi’an (710032 | | 徐重明 | Zhang Mei, Zhang Zhonghai, Xia Tian, et al Department of TCM, Xijing Hospital, the Fourth Military Medical University, Xi’an (710032 | | 于文彬 | Zhang Mei, Zhang Zhonghai, Xia Tian, et al Department of TCM, Xijing Hospital, the Fourth Military Medical University, Xi’an (710032 |
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| 中文摘要: |
| 目的：观察四君子汤对脾虚患者血清可溶性细胞粘附分子－１（ｓＩＣＡＭ １）和单核细胞功能的影响。方法：采用酶联免疫吸附法和改良噻唑蓝法对６６例脾虚患者血清ｓＩＣＡＭ １和白细胞介素 １５（ＩＬ １５）及单核细胞抗体依赖性细胞介导的细胞毒反应（ＡＤＣＣ）进行检测。结果：脾虚患者血清ｓＩＣＡＭ １水平升高，ＩＬ １５分泌减少，ＡＤＣＣ功能下降，表现为免疫功能低下，经过四君子汤治疗后，上述指标恢复正常。结论：四君子汤健脾益气可提高机体免疫功能 |
| 英文摘要: |
| Objective: To study the effect of Sijunzi Decoction (SJZD) on serum soluble intercellular adhesive molecule 1 (sICAM 1), interleukin 15 (IL 15) and monocyte antibody dependent cell mediated cytotoxicity (ADCC) in patients of Spleen Deficiency. Methods: Serum sICAM 1, IL 15 and monocyte ADCC of 66 Spleen Deficiency patients were determined by enzyme linked immunosorbent assay and modified thiazole blue test. Results: Serum sICAM 1 of Spleen Deficiency patients increased, IL 15 secretion decreased and monocyte ADCC function reduced, which displayed as lowered immune function. After SJZD treatment, all the above mentioned parameters were normalized. Conclusion: SJZD could enhance immune function of organism by strengthening Spleen and tonifying Qi. |
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