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李雪荣,陈志坚.中药多动宁与西药利他林治疗儿童多动综合征临床对照观察[J].,1999,(7):410-411
中药多动宁与西药利他林治疗儿童多动综合征临床对照观察
Clinical Comparative Observation on Duodongning and Ritalin in Treating Child Hyperkinetic Syndrome
  
DOI:
中文关键词:  儿童多动综合征  中药多动宁  利他林  临床对照观察
英文关键词:child hyperkinetic syndrome  Duodongning  Ritalin  clinical comparative observation
基金项目:
Author NameAffiliation
Li Xuerong  
陈志坚  
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中文摘要:
      目的:探讨中药多动宁治疗儿童多动综合征的疗效及副作用。方法:用双盲法对照研究中药多动宁(治疗组)与西药利他林(对照组)对儿童多动综合征的疗效及副作用。结果:治疗组37例,显效17例(459%),有效16例(432%)。对照组33例,显效15例(455%),有效14例(424%)。Conners多动指数:对照组治疗前为201±083,治疗后为117±076;治疗组治疗前为207±091,治疗后为147±079;两组疗效及多动指数比较均无显著性差异(P>005)。副作用(主要为食欲减退):治疗组有3例,症状较轻;对照组有7例,症状较严重。结论:两组患者临床疗效相似,而副作用利他林高于中药多动宁。
英文摘要:
      Objective: To study the effect and side effect of Duodongning (DDN), a Chinese herbal preparation, in treating child hyperkinetic syndrome. Methods: Double blind method was used in observation on effect of DDN and compared with that of Ritalin. Results: In the 37 patients treated with DDN, 17 (45.9%) were markedly effective and 16 (43.2%) were effective. In the 33 Patients treated with Ritalin, the respective case numbers were 15 (45.5%) and 14 (42.4%). The Conners Hyperactive Index of the DDN group before treatment was 2.01±0.83, and after treatment 1.17±0.76,while that of the Ritalin group was 2.07±0.91 before treatment and 1.47±0.79 respectively after treatment. There were no significant difference between the two groups both in effect and in Conner Index, P>0 05. The main side effect was lack of appetite, it revealed in 3 cases of the DDN group and 7 cases of the Ritalin group, and was severer in the latter. Conclusion: The effect of DDN and Ritalin were not different significantly, but the side effect of Ritalin was severer than that of DDN.
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