| 余月明,崔建强,张凡,王涛,张人杰,郭东阳,陈昭颉.健脾利湿、活血化浊中药延缓慢性肾功能衰竭[J].,2000,(10):727-728 |
| 健脾利湿、活血化浊中药延缓慢性肾功能衰竭 |
| Chinese Drugs for Invigorating Spleen to Remove Dampness, Activating Blood Circulation to Eliminate Turbid in Retarding Progression of Chronic Renal Failure |
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| DOI： |
| 中文关键词: 慢性肾功能衰竭 健脾利湿 活血化浊 肾功能 血脂 |
| 英文关键词:chronic renal failure invigorating Spleen to remove Dampness activating blood circulation to eliminate Turbid renal function blood lipid |
| 基金项目: |
| Author Name | Affiliation | | 余月明 | YU Yueming, CUI Jianqiang, ZHANG Fan, et al. Department of Nephrology, General Hospital of Chengdu Military Region, Chengdu (610083 | | 崔建强 | YU Yueming, CUI Jianqiang, ZHANG Fan, et al. Department of Nephrology, General Hospital of Chengdu Military Region, Chengdu (610083 | | 张凡 | YU Yueming, CUI Jianqiang, ZHANG Fan, et al. Department of Nephrology, General Hospital of Chengdu Military Region, Chengdu (610083 | | 王涛 | YU Yueming, CUI Jianqiang, ZHANG Fan, et al. Department of Nephrology, General Hospital of Chengdu Military Region, Chengdu (610083 | | 张人杰 | YU Yueming, CUI Jianqiang, ZHANG Fan, et al. Department of Nephrology, General Hospital of Chengdu Military Region, Chengdu (610083 | | 郭东阳 | YU Yueming, CUI Jianqiang, ZHANG Fan, et al. Department of Nephrology, General Hospital of Chengdu Military Region, Chengdu (610083 | | 陈昭颉 | YU Yueming, CUI Jianqiang, ZHANG Fan, et al. Department of Nephrology, General Hospital of Chengdu Military Region, Chengdu (610083 |
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| 中文摘要: |
| 目的 :观察健脾利湿、活血化浊中药对慢性肾功能衰竭 (CRF)进展的延缓作用。方法 :39例患者分为两组 ,A组采用低蛋白饮食、控制高血压治疗及对症处理 ;B组在A组治疗的基础上加用健脾利湿、活血化浊中药治疗 ,并同时观察两组患者治疗前后肾功能、血脂变化 ,计算血清肌酐倒数与时间的直线回归斜率作为评估CRF的进展速度。结果 :治疗后B组血清肌酐、血尿素氮明显低于A组 (P <0 0 5) ,而高密度脂蛋白明显高于A组 (P <0 0 1) ;直线回归斜率两组间差异有显著性 (P <0 0 1)。结论 :在低蛋白饮食和控制高血压基础上加用健脾利湿、活血化浊中药可使慢性肾功能衰竭进展速度明显延缓 |
| 英文摘要: |
| Objective: To investigate the effect of Chinese drugs (CD) for invigorating Spleen to remove dampness, activating blood circulation to eliminate Turbid in retarding progression of chronic renal failure (CRF). Methods: Thirty nine patients with CRF were divided into two groups randomly, 18 patients in the control group were treated with low protein diet and controlling blood pressure and 21 patients in the CD group were treated similarly with that of the control group but with additional CD. Levels of serum creatinine (SCr), blood urea nitrogen (BUN), blood albumin (Alb), cholesterol (CH), triglyceride (TG), high density lipoprotein (HDL) and hemoglobin (Hb) were checked every 2 months, and the rate of progression of CRF was estimated by slope of the creatinine reciprocal (1/SCr) with time (month). Results: Levels of SCr and BUN in the CD group were significantly lower and HDL markedly higher than those in the control group, P<0 05. Mean slopes of the creatinine reciprocal with time in the two groups was significantly different, P<0 01. Conclusion: Additional CD treatment based upon the protein diet and controlling blood pressure could retard the progression process of CRF evidently. |
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