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薄守波,鞠建伟,初冬,曲桂梅,张燕,付俊峰.肾宁合剂治疗IgA肾病的临床研究[J].,2000,(10):729-730
肾宁合剂治疗IgA肾病的临床研究
Clinical Study on Shenning Mixture in Treating IgA Nephropathy
  
DOI:
中文关键词:  IgA肾病  肾宁合剂  血尿  蛋白尿  免疫球蛋白
英文关键词:IgA nephropathy  Shenning Mixture  hematuria  albuminuria  immune globulin
基金项目:烟台市1997科技发展计划第一批项目!(No.40)
Author NameAffiliation
薄守波 BO Shoubo, JU Jianwei, CHU Dong, et al. The Yuhuangding Hospital, Yantai City, Shandong (264000 
鞠建伟 BO Shoubo, JU Jianwei, CHU Dong, et al. The Yuhuangding Hospital, Yantai City, Shandong (264000 
初冬 BO Shoubo, JU Jianwei, CHU Dong, et al. The Yuhuangding Hospital, Yantai City, Shandong (264000 
曲桂梅 BO Shoubo, JU Jianwei, CHU Dong, et al. The Yuhuangding Hospital, Yantai City, Shandong (264000 
张燕 BO Shoubo, JU Jianwei, CHU Dong, et al. The Yuhuangding Hospital, Yantai City, Shandong (264000 
付俊峰 BO Shoubo, JU Jianwei, CHU Dong, et al. The Yuhuangding Hospital, Yantai City, Shandong (264000 
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中文摘要:
      目的 :研究肾宁合剂对IgA肾病临床治疗作用。 方法 :采用随机分组法分别用肾宁合剂及强的松治疗 ,同时观察两组患者 (各 35例 )临床症状、体征、血尿、蛋白尿及免疫球蛋白等指标。结果 :完全缓解率和总有效率治疗组分别为 4 5 7%、97 1% ,对照组分别为 8 6% ,37 1% ,治疗组疗效明显优于对照组(P <0 0 1)。治疗组血尿、蛋白尿改变明显优于对照组 (P <0 0 1和P <0 0 5)。治疗组血清IgA治疗后较治疗前明显降低 (P <0 0 5)。结论 :肾宁合剂对IgA肾病的血尿及蛋白尿有明显治疗作用
英文摘要:
      Objective: To study the clinical therapeutic effect of Shenning Mixture (SNM) in treating IgA nephropathy. Methods: Patients were treated separately with SNM or prednisone by randomized grouping. The criteria, including clinical symptoms, signs, hematuria, albuminuria and immune globulin were observed. Results: The total effective rate and the complete remission rate in the SNM group were 97.1% and 45.7% respectively, while in the control group, they were 37.1% and 8.6% respectively. Comparison of the two groups showed that the therapeutic effect in the former was better than that in the latter significantly, P<0 01. The hematuria and albuminuria extenuated and serum IgA lowered more significantly in the SNM group than those in the control group (P<0 05, P<0 01). Conclusion: SNM has obvious therapeutic effect on the hematuria and albuminuria in treating IgA nephropathy.
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