薄守波,鞠建伟,初冬,曲桂梅,张燕,付俊峰.肾宁合剂治疗IgA肾病的临床研究[J].,2000,(10):729-730 |
肾宁合剂治疗IgA肾病的临床研究 |
Clinical Study on Shenning Mixture in Treating IgA Nephropathy |
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DOI: |
中文关键词: IgA肾病 肾宁合剂 血尿 蛋白尿 免疫球蛋白 |
英文关键词:IgA nephropathy Shenning Mixture hematuria albuminuria immune globulin |
基金项目:烟台市1997科技发展计划第一批项目!(No.40) |
Author Name | Affiliation | 薄守波 | BO Shoubo, JU Jianwei, CHU Dong, et al. The Yuhuangding Hospital, Yantai City, Shandong (264000 | 鞠建伟 | BO Shoubo, JU Jianwei, CHU Dong, et al. The Yuhuangding Hospital, Yantai City, Shandong (264000 | 初冬 | BO Shoubo, JU Jianwei, CHU Dong, et al. The Yuhuangding Hospital, Yantai City, Shandong (264000 | 曲桂梅 | BO Shoubo, JU Jianwei, CHU Dong, et al. The Yuhuangding Hospital, Yantai City, Shandong (264000 | 张燕 | BO Shoubo, JU Jianwei, CHU Dong, et al. The Yuhuangding Hospital, Yantai City, Shandong (264000 | 付俊峰 | BO Shoubo, JU Jianwei, CHU Dong, et al. The Yuhuangding Hospital, Yantai City, Shandong (264000 |
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中文摘要: |
目的 :研究肾宁合剂对IgA肾病临床治疗作用。 方法 :采用随机分组法分别用肾宁合剂及强的松治疗 ,同时观察两组患者 (各 35例 )临床症状、体征、血尿、蛋白尿及免疫球蛋白等指标。结果 :完全缓解率和总有效率治疗组分别为 4 5 7%、97 1% ,对照组分别为 8 6% ,37 1% ,治疗组疗效明显优于对照组(P <0 0 1)。治疗组血尿、蛋白尿改变明显优于对照组 (P <0 0 1和P <0 0 5)。治疗组血清IgA治疗后较治疗前明显降低 (P <0 0 5)。结论 :肾宁合剂对IgA肾病的血尿及蛋白尿有明显治疗作用 |
英文摘要: |
Objective: To study the clinical therapeutic effect of Shenning Mixture (SNM) in treating IgA nephropathy. Methods: Patients were treated separately with SNM or prednisone by randomized grouping. The criteria, including clinical symptoms, signs, hematuria, albuminuria and immune globulin were observed. Results: The total effective rate and the complete remission rate in the SNM group were 97.1% and 45.7% respectively, while in the control group, they were 37.1% and 8.6% respectively. Comparison of the two groups showed that the therapeutic effect in the former was better than that in the latter significantly, P<0 01. The hematuria and albuminuria extenuated and serum IgA lowered more significantly in the SNM group than those in the control group (P<0 05, P<0 01). Conclusion: SNM has obvious therapeutic effect on the hematuria and albuminuria in treating IgA nephropathy. |
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