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戚广崇,陆寄坤,阚钦林,李其信,王正民,李军,张国兆,胡全林,徐文友,包正荣.通精冲剂与手术治疗精索静脉曲张不育症的临床研究[J].,2001,(6):412-415
通精冲剂与手术治疗精索静脉曲张不育症的临床研究
Comparative Clinical Study on Treatment of Varicocele Caused Infertility by Tongjing Granule and Surgical Operation
  
DOI:
中文关键词:  精索静脉曲张  不育症  通精冲剂  活血化瘀  精液电脑自动分析仪  精子运动参数
英文关键词:varicocele  infertility  Tongjing granule  activate blood circulation to remove stasis  computerized automatic seminal analyser  the sperm sports data
基金项目:上海市医学领先学科基金中西医结合不育症特色专科项目!课题(No .962 0 0 6)
Author NameAffiliation
QI Guang chong 上海市北站医院男子不育症专科 
LU Ji kun 上海市北站医院男子不育症专科 
KAN Qin lin 上海市北站医院男子不育症专科 
李其信 上海市北站医院男子不育症专科 
王正民 上海市北站医院男子不育症专科 
李军 上海市北站医院男子不育症专科 
张国兆 上海市北站医院男子不育症专科 
胡全林 上海市北站医院男子不育症专科 
徐文友 广西防城港市人民医院男科 
包正荣 上海市金山区中心医院男科 
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中文摘要:
      目的 :进一步观察通精冲剂治疗精索静脉曲张不育症的治疗效果。方法 :将 75例Ⅱ (中度 )~Ⅲ度 (重度 )精索静脉曲张伴精液质量异常的不育患者 ,分成中药治疗组 (4 4例 )与手术治疗组 (31例 )进行对照研究。中药组采用通精冲剂治疗 ,手术组采用精索静脉高位结扎术或 (和 )加腹壁下静脉转流术。所有患者均定期复诊或随访。用精液电脑自动分析仪 (CASA)对两组治疗前后的精子计数、活率、各项运动参数以及配偶怀孕等情况进行观察。结果 :治疗前中药组与手术组各项指标大多差异无显著性 ,中药组精子密度、运动精子数、前向运动精子数等低于手术组 ;治疗后中药组CASA分析 ,精子质量明显改善 ,而手术组手术前后差异无显著性 (P >0 0 5)。结论 :用通精冲剂治疗精索静脉曲张引起不育症 ,可达到手术治疗的临床效果 ,而且精子运动参数改善明显。表明手术治疗仅单纯改善局部情况 ,而中药通精冲剂治疗还能进一步调节全身功能。
英文摘要:
      Objective: To observe the effect of Tongjing granule (TJG) in treating varicocele caused infertility. Methods: Comparative observation was carried on 75 cases of male infertility caused by moderate or severe varicocele with abnormal semen, they were divided into two groups: the 44 patients in the TCM group treated with TJG and the 31 patients in the operation group treated by surgical operation (high ligation of spermatic vein and/or inferior epigastric venous bypass). All patients were followed up periodically to observe the amount, survival rate and activity of sperm by computerized automatic seminal analyser (CASA), as well as the occurrence of pregnancy in their partner. Results: No significant difference was found in various parameters between the two groups. After treatment, the improvement of seminal density, amount of active sperms and forward moving sperms were lower in the TCM group than that in the operation group, but according to CASA, the improvement of TCM group is better than that of operation group. There was insignificance in the operation group between pre and post treatment, P>0 05.Conclusion: TJG could treat the varicocele caused infertility with the clinical effect similar to the surgical operation, and was superior in improving motility of sperm. It indicates that surgical operation could only improve the local lesion, but TJG could modulate the general condition of patients also.
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