| 王悦,李鲁,何炳荣,张融碧.中西降压药的成本—效果分析综合评价[J].,2001,(9):663-666 |
| 中西降压药的成本—效果分析综合评价 |
| CEA Comprehensive Evaluation for Western and Traditional Chinese Hypotensive Drugs |
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| DOI： |
| 中文关键词: 降压药 高血压 生活质量 成本—效果分析 综合评价 |
| 英文关键词:hypotensive drug hypertension quality of life cost effectivenessanalysis comprehensive evaluation |
| 基金项目: |
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| 中文摘要: |
| 目的 :观察 4种降压药的降压效果、症状改善、不良反应及对高血压病患者生活质量 (QOL)的影响 ,并对 4种药物作成本—效果分析 (CEA)。方法 :将 2 92例轻、中度高血压病患者 ,随机分成 4组 ,疗程均为 6周。QOL测定采用SF 36量表 ,CEA综合评价采用效果决策模式。结果 :按综合评价得分高低依次为 :吲达帕胺 (3 65 )、复方羚角降压片 (3 5 5 )、苯磺酸氨氯地平 (2 90 )、盐酸苯那普利 (2 35 )。结论 :4种降压药不仅有良好的降压效果 ,改善症状积分、且不良反应也较少 ;评价和选择降压药物 ,应结合QOL测评 ;CEA综合评价表明复方羚角降压片列第 2位 ,提示应重视中药降压治疗。 |
| 英文摘要: |
| Objective: To make a cost effectiveness analysis (CEA) comprehensive evaluation for 4 hypotensive drugs, by observing the effects of drugs on blood pressure lowering, symptom improving, and adverse effect and quality of life (QOL) influencing. Methods: Two hundred and ninety two patients with mild to moderate hypertension were divided into 4 groups at random and treated with compound Lingjiao Jiangya Pill, benazepril, amlodipine and indapamide respectively with a therapeutic course of 6 weeks. QOL was measured with FS 36 questionnaire and efficacy policy model was applied for comprehensive evaluation of CEA. Results: Through CEA a comprehensive evaluation was made in order as follows: indapamide 3.65 which was the best, and then Lingjiao Jiangya Pill 3.55, amlodipine 2.90 and benazepril 2.35. Conclusion: The 4 drugs can not only lower blood pressure but also improve clinical symptoms with less adverse effect. It is of great practical significance to evaluate hypotensive drugs by combining QOL appraisal. The position of Lingjiao Jiangya Pill in CEA order suggests that more attention should be paid to herbal hypotensive drugs. |
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