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罗成群,周建大,贺全勇,周鹏翔,朱颉,李萍,彭浩,罗骜.中药合剂对特重度烧伤患者免疫功能的影响[J].,2002,(8):594-596
中药合剂对特重度烧伤患者免疫功能的影响
Effect of Clinese Drugs Mixture on Immune Function of Patients with Extremely Severe Burn
  
DOI:
中文关键词:  烧伤  中药合剂  免疫功能
英文关键词:burn  Chinese drugs mixture  immune function
基金项目:湖南省卫生厅中医药科研基金资助项目 (No.2 0 32 8)
Author NameAffiliation
LUO Cheng qun 中南大学湘雅三医院烧伤整形外科 北京100045 
ZHOU Jian da 中南大学湘雅三医院烧伤整形外科 北京100045 
HE Quan yong 中南大学湘雅三医院烧伤整形外科 北京100045 
周鹏翔 中南大学湘雅三医院烧伤整形外科 北京100045 
朱颉 中南大学湘雅三医院烧伤整形外科 北京100045 
李萍 中南大学湘雅三医院烧伤整形外科 北京100045 
彭浩 中南大学湘雅三医院烧伤整形外科 北京100045 
罗骜 中南大学湘雅三医院烧伤整形外科 北京100045 
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中文摘要:
      目的 :探讨中药合剂清火败毒饮对特重度烧伤患者免疫功能的调理作用。方法 :将 30例特重度烧伤患者分成两组 ,两组均进行常规治疗 ,中药组加用中药合剂治疗 ,治疗前及治疗后各时间段测定外周血中T淋巴细胞亚群和体液免疫功能 ,并判定两组治疗效果。结果 :与对照组比较 ,中药组CD3、CD4 、CD4 /CD8值下降程度轻 (P <0 0 5或P <0 0 1) ,CD8升高程度轻 (P <0 0 1) ,但均恢复快 ;IgG、IgA、IgM、C3、C4 值均有不同程度降低 (P <0 0 5或P <0 0 1) ,但中药组回升早 ,恢复快而好。结论 :中药合剂对特重度烧伤患者的细胞、体液免疫功能均有调理作用。
英文摘要:
      Objective: To study the regulatory effect of Qinghuo Baidu Yin (QHBDY, a mixture prepared with Chinese drugs) on immune function of patients with extremely severe burn (ESB). Methods: Thirty patients with ESB were divided into two groups, conventional therapy was given to both groups, but QHBDY was given to the treated group additionally. Immunological indices, including peripheral blood T lymphocyte subsets, immunoglobin (IgG, IgA and IgM) and complement (C 3 and C 4) were determined 3 weeks after treatment to evaluate and compare the therapeutical effect in the two groups. Results: Compared with the control group, CD 3, CD 4, CD 4/CD 8, immuoglobin (IgG, IgA and IgM) and complement (C 3 and C 4) levels were markedly decreased in degree, and recovered earlier and quicker, with CD 8 increased mildly (P<0 01) and turned back more quickly. And so did the parameters of the treated group in comparing with that of the control group at anytime (P<0 05 or P<0 01). Conclusion: Chinese drugs mixture shows the regulatory effect on both cellular and humoral immune function in patients with ESB.
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