| 李秀惠,张可,胡建华,郭新会,胡中杰,扬宇,梁连春.中西医结合治疗SARS的临床疗效观察[J].,2003,(7):489-491 |
| 中西医结合治疗SARS的临床疗效观察 |
| Clinical Observation on Effect of Treatment of Severe Acute Respiratory Syndrome (SARS) by Integrative Chinese and Western Medicine |
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| DOI： |
| 中文关键词: 中西医结合治疗 严重急性呼吸综合征 T细胞亚群 |
| 英文关键词:integrative Chinese and western medicine severe acute respiratory syndrome T subcytes |
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| 中文摘要: |
| 目的:分析中西结合治疗严重急性呼吸综合征（SARS）的疗效。方法:对2003年3月11日—4月30日在我院用中西医结合治疗（中西医组）的65例SARS患者,并与单用西药治疗（西药组）的37例作对照,还测定了T细胞亚群（CD4+）。结果:中西医组65例,其中普通型52例,治愈51例（98.1％）,好转1例;重型13例,治愈9例（69.2％）,好转2例（15.4％）,死亡2例（15.4％）。西药组37例,其中普通型18例,治愈16例（88.9％）,好转2例;重型19例,治愈10例（52.6％）,死亡9例（47.4％）,两组比较差异接近显著性（P=0.061）。CD4+:普通型患者中西医组治疗前为（360±247）个细胞/μl,治疗后为（563±479）个细胞/μl（P<O.05）,西药组治疗前为（331±193）细胞个/μl,治疗后为（772±354）细胞个/μl（P<O.05）;重型患者CD4+两组治疗前后比较差异均无显著性（P>0.05）,中西医组治疗前后CD4+差值显著高于西药组（P<0.05）。结论:初步观察中西医结合治疗在改善SARS患者的预后,降低患者的病死率有影响,同时能帮助患者恢复免疫功能。 |
| 英文摘要: |
| Objective: To evaluate the efficacy of integrative Chinese and western medicine (ICWM) in treating severe acute respiratory syndrome (SARS). Methods: Analysis was conducted on 102 in-patients of SARS hospitalized from March 11,2003 to April 30,2003. Results:In the 65 patients treated with ICWM, 51 of the 52 patients (98.1%) of ordinary type were cured with no death, and 9 of the 13 patients (69.2%) of severe type were cured with 2 (15.4% ) died. The 37 patients, 18 of ordinary type and 19 of severe type were treated with western medicine (WM) alone. Of the ordinary type, 16 (88.9%) cured, and of the severe type, 10 (52.6%) cured and 9 (47.4% ) died. In comparing between the two groups (P = 0.061), the difference was close to be significant. Taking into consideration on the factor that the sample was small, further evaluation was needed by increasing the number of patients in the sample for observation. Moreover, immune function examination showed that the CD4 +lymphocyte in patients of ordinary type after ICWM treatment increased from 360 ±247/μl to 563 ±479/μl(P<0.05) and after WM treatment, increased from 331±193/μl to 772±354/μl (P< 0.05) . While in patients of severe type, it increased after ICWM treatment from 331±193/μl to 525±490/μl. Comparison of CD4±after treatment between the two groups showed significantly different (P < 0.05). Conclusion:The preliminary observation showed that ICWM treatment, as compared with WM treatment, was better in improving the prognosis and reducing the mortality rate of SARS patients, and could benefit the recovery of their immune functions. |
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