刘煜敏,章军建,姜健,黄朝云,任善玲,高永哲.当归注射液治疗急性脑梗塞患者的临床疗效观察[J].,2004,(3):205-208 |
当归注射液治疗急性脑梗塞患者的临床疗效观察 |
Observation on Clinical Effect of Angelica Injection in Treating Acute Cerebral Infarction |
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DOI: |
中文关键词: 当归注射液 急性脑梗塞 神经功能缺损评分 Barthel指数评分 |
英文关键词:Angelica injection acute cerebral infarction neuro-function deficit scoring Barthel index scoring |
基金项目:国家自然科学基金项目(No.30270483);湖北省自然科学基金项目(No.99J116)资助 |
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中文摘要: |
目的 研究当归注射液对急性脑梗塞的治疗效果。方法 急性脑梗塞患者1 404例,分别用当归(当归组,692例)、低分子右旋糖酐(低右组,322例)、复方丹参注射液(丹参组,390例)治疗,以入院前后CT扫描梗塞灶体积,治疗后第1、3、7、15、25天临床神经功能缺损评分以及停药后2周末临床疗效评定,Barthel指数评分作为观察指标。结果 3组治疗总有效率分别为78.7%、59.3%、63.6%,当归组总有效率显著高于其他两组(P<0.05);神经功能缺损评分及Barthel指数评分改善当归组优于丹参组及低右组(25天时P<0.01),梗塞灶体积缩小幅度当归组大于低右组(P<0.01)。结论 当归注射液对急性脑梗塞具有明显疗效。 |
英文摘要: |
To study the therapeutic effect of Angelica Injection (AI) in treating acute cerebral infarction (ACI). Methods One thousand four hundred and four patients, who were treated with AI (692 patients in Group A), compound salvia (390 patients in Group B) and low molecular dextran injection (322 patients in Group C) respectively. Indexes such as CT scanning on infarcted volume, scoring of clinical neuro-function deficit taking on the 1st, 3rd, 7th, 15th and 25th day, clinical therapeutic effectiveness evaluated by the end of the 2nd week and the improvement of Barthel index scores were observed. Results The total effective rate in Group A, B and C was 78.7% , 63.6% and 59.3% respectively, that in Group A was significantly higher than in the other two groups (P<0.05). The improvement of neuro-function deficit scores and Barthel scores in Group A were better than those in Group B and C (on the 25th day, P<0.01), and the decrement of infarcted volume in Group A was larger than that in Group C (P<0.01). Conclusion AI has evident therapeutic effect in treating ACI. |
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