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Author Name	Affiliation
GAO Zhi-qing	上海中医药大学附属龙华医院肾内科上海 200032
DENG Yue-yi	上海中医药大学附属龙华医院肾内科上海 200032
WANG Lin	上海中医药大学附属龙华医院肾内科上海 200032
陈以平	上海中医药大学附属龙华医院肾内科上海 200032

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中文摘要:

近年来,慢性尿酸性肾病的实验研究逐渐增多,人们主要从基因重组、抑制尿酸排泄、促进血尿酸产生几方面来复制动物模型。中医药在降低血尿酸、调整细胞因子水平、延缓肾间质纤维化方面显现出较好疗效,但尚待进一步加大对中药或其提取成分的研究。本文就上述内容进行了综述。

英文摘要:

Following contents were reviewed in this article: More and more experimental studies related with chronic uratic nephropathy were carried out in recent years. In most of these studies, the animal models were established mainly from viewpoints of gene recombination, urinary uric acid inhibition and blood uric acid production promoting. TCM showed good effects in lowering blood uric acid, regulating levels of cytokines and postponing interstitial fibrosis. However, further studies on Chinese herbs and their extracts is necessary.

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