| 封颖璐,凌昌全,李柏,陈喆,俞超芹.中西医结合防治经动脉化疗栓塞术后综合征的研究[J].,2005,(6):534-536 |
| 中西医结合防治经动脉化疗栓塞术后综合征的研究 |
| Clinical Study on Integrative Medicine for Preventing and Treating Post-Transcatheter Arterial Chemoembolization |
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| DOI： |
| 中文关键词: 经动脉化疗栓塞术 地塞米松 人参皂甙 |
| 英文关键词:post-transcatheter arterial chemoembolization dexamethasone ginsenosides |
| 基金项目:国家自然科学杰出青年基金资助项目(No.30025045) |
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| 中文摘要: |
| 目的观察人参皂甙及小剂量糖皮质激素防治经动脉化疗栓塞术(transcatheterarterialchemoembolization,TACE)后综合征的效果。方法采用随机、双盲对照方法,将80例原发性肝癌患者分为4组,每组20例。A组用安慰剂,B组用地塞米松,C组用人参皂甙,D组用地塞米松加入参皂甙。观察TACE后临床症状、理化指标等变化。结果地塞米松加人参皂甙可显著降低恶心、呕吐、发热等症状的发生率及症状持续的中位时间,并具有缓解骨髓抑制的作用。结论地塞米松加人参皂甙可有效防治TACE栓塞后综合征。 |
| 英文摘要: |
| Objective To observe the effects of ginsenosides (GS) and low dose glucocorticoid for preventing and treating the post-transcatheter arterial chemoembolization (TACE) syndrome. Methods Adopting randomized, double blinded, controlled method, 80 patients with primary liver cancer were divided into 4 groups, placebo group, dexamethasone (Dex) group, Ginsenosides (GS) group, and Dex combined with GS group to observe the clinical effect of the patients after TACE. Results Dex combined with GS could markedly lower the occurrence of nausea, vomiting, fever and pain, and the median time of symptoms persistence, also alleviate the bone marrow inhibition of chemotherapy. Conclusion Dex combined with GS could effectively prevent and treat TACE syndrome. |
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