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刘维,张磊,徐照.痹祺胶囊治疗类风湿关节炎临床观察[J].,2006,(2):157-159
痹祺胶囊治疗类风湿关节炎临床观察
Clinical Observation on Treatment of Rheumatoid Arthritis with Biqi Capsule
  
DOI:
中文关键词:  痹祺胶囊  类风湿关节炎  湿热痹阻证  气虚血瘀证
英文关键词:Biqi capsule  rheumatoid arthritis  dampness-heat blockage syndrome  Qi deficiency and blood stasis syndrome
基金项目:
Author NameAffiliation
LIU Wei 天津中医学院第一附属医院风湿科 天津300193 
ZHANG Lei 天津中医学院第一附属医院风湿科 天津300193 
XU Zhao 天津中医学院第一附属医院风湿科 天津300193 
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中文摘要:
      目的研究痹祺胶囊治疗类风湿关节炎(rheumatoidarthritis,RA)的临床疗效及适应证。方法RA患者随机分为两组,各71例,其中每组符合湿热痹阻证者36例,符合气虚血瘀证者35例;治疗组采用痹祺胶囊治疗,对照组采用非甾体抗炎药普威片(主要成分为尼美舒利)治疗,用药8周。结果治疗组71例,总有效率66.2%(47例),仅有1例发生轻度不良反应。其中湿热痹阻证36例,总有效率为41.7%;气虚血瘀证35例,总有效率达91.4%,气虚血瘀证疗效好于湿热痹阻证(P<0.05)。对照组71例,总有效率60.6%(43例);其中湿热痹阻证36例,总有效率为63.9%;气虚血瘀证35例,总有效率达57.1%;两证型疗效比较差异无显著性(P>0.05)。结论痹祺胶囊是治疗RA安全有效的药物,尤其对气虚血瘀证疗效更佳。
英文摘要:
      Objective To study the indication and clinical efficacy of Biqi capsule (BC) in treating patients with rheumatoid arthritis (RA). Methods One hundred and forty-two RA patients were randomly divided into the BC treated group and the control group treated with nimesulide tablet (NT). There were 36 patients with dampness-heat blockage syndrome type and 35 patients with Qi deficiency and blood stasis syndrome type in each group. The treatment course lasted for 8 weeks. Results The total effective rate in the BC group was 66.2% (47 cases), while that in the control group was 60.6% (43 cases). The total effective rate in the patients with Qi deficiency and blood stasis syndrome type in the BC group was 91.4%, superior to that with dampness-heat blockage type (41.7%). Only one patient showed mild adverse reaction in the BC group. Conclusion BC is a kind of safe and effective herble medicine for treatment of RA, especially for those of Qi deficiency and blood stasis syndrome type.
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