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Author Name	Affiliation
SONG Ai-li	山东中医药大学附属医院乳腺外科
LIU Xiao-fei	山东中医药大学
LI Jing-wei	山东中医药大学附属医院乳腺外科
孙贻安	山东中医药大学附属医院乳腺外科

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中文摘要:

乳腺癌的防治日益受到重视,“乳腺癌多阶段发展模式”为在乳腺癌癌前病变阶段阻断和逆转提供了依据。中医药在抑制血管生成、促进细胞凋亡、调节内分泌系统和抑制癌基因表达方面对癌前病变的干预作用。提出中医应从认识疾病本质,制订乳腺癌癌前病变中医诊疗标准和拓展治疗目的,研究中药对乳腺癌癌前变的干预作用机理的角度进行研究。

英文摘要:

Prevention and treatment of mammary cancer has been taken into great account recently. “Muti-stage developing mode" provides the basis for interrupting and reversing precancerous changes. Traditional Chinese medicine (TCM) has shown effects on precancerous changes through inhibiting angiogenesis, promoting apoptosis, modulating endocrine system and restraining oncogene expression. It was stressed in this review that TCM should study the precancerous change of mammary cancer from the aspects of recognizing the essence of precancerous changes of mammary cancer, formulating the standard of TCM diagnosis and treatment, widening the aim of treatment, and focusing on the mechanism of Chinese herbal medicine in intervening it.

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