| 张红武,王纯莹,许慧宁,赵秀丽,代青湘,李军,杜欣柏,宋志强,韩国玲,刘桂兰,李平善,林华华.氟西汀联合中、藏药治疗高原地区老年抑郁症的临床观察[J].,2006,(3):202-204 |
| 氟西汀联合中、藏药治疗高原地区老年抑郁症的临床观察 |
| Clinical Study on Effect of Fluoxetine Combined with Chinese Medicine o r Tibetan Drugs in Treating Senile Depression in Plateau District |
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| DOI： |
| 中文关键词: 氟西汀 三普心脑欣胶囊 逍遥丸 高原地区 老年抑郁症 |
| 英文关键词:fluoxetine Sanpu Xinnao Xin granule X iaoyao pill plateau senile depression |
| 基金项目:卫生部保健局专项资助项目(No.2002-9) |
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| 中文摘要: |
| 目的比较观察单用氟西汀和氟西汀加中、藏药治疗高原地区老年抑郁症的疗效和不良反应。方法对高原地区(海拔2260~3200m)符合CCMD-3抑郁症发作诊断标准的患者90例,随机分为3组,分别给予氟西汀(西药组)、氟西汀加中药逍遥丸(加中药组)和氟西汀加藏药三普心脑欣胶囊(加藏药组)治疗,疗程均为6周,并用汉米尔顿抑郁量表(HAMD)和不良反应量表(TESS)进行疗效评定。结果3组疗效比较差异无显著性。加中药和加藏药组不良反应较西药组少,差异有显著性(P<0.05)。结论三普心脑欣胶囊和逍遥丸能提高高原地区老年抑郁症患者对氟西汀的耐受性。 |
| 英文摘要: |
| ObjectiveTo compare the effect and side-ef fect of fluoxetine and combination of fluoxetine and Chinese or Tibetan medicine in treating senile depression in plateau district. Methods Ninety pat ients with diagnosis of senile depression conformed to CCMD-3 standard, i n plateau district of 2260～3200 m altitude were randomly divided into t h ree groups and treated with fluoxetine (group A), fluoxetine plus Sanpu Xinnao Xin granule (group B) and fluoxetine plus Xiaoyao pill (group C), resp ectively, 30 cases in each group. Therapeutic effects were evaluat ed with Hamilton’s depressive scale (HAMD) and treatment emergent symptom scale (TESS) after 6 weeks treatment. Results There was no significant difference in the therapeutic effects between the three gr oups. The adverse reaction in Group B and C was less than that in Group A (P<0.01). Conclusion Sanpu Xinnao Xin granule and Xiaoyao pill can raise the tolerance of patients with senile depression in plateau area against the adverse reaction of fluoxetine. |
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