| 林丽珠,周岱翰,郑心婷.中医药提高晚期非小细胞肺癌患者生存质量的临床观察[J].,2006,(5):389-393 |
| 中医药提高晚期非小细胞肺癌患者生存质量的临床观察 |
| Effect of Traditional Chinese Medicine in Improving Quality of Life of Patients with Non-small Cell Lung Cancer in Late Stage |
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| DOI： |
| 中文关键词: 中医药疗法 中西医结合疗法 非小细胞肺癌 生存质量 |
| 英文关键词:traditional Chinese medicinal therapy therapy of integrative medicine non-small cell lung cancer quality of life |
| 基金项目:国家科技部“十五”重点攻关课题(No.2001BA701A15b) |
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| 中文摘要: |
| 目的观察中医药疗法提高Ⅲ、Ⅳ期非小细胞肺癌(NSCLC)患者生存质量的作用,确立中医药治疗晚期NSCLC的治疗方案。方法将6所医院294例NSCLC患者随机分为中医组(99例,中医辨病和辨证治疗)、西医组(92例,化疗)和中西医组(103例,中医辨病辨证治疗联合化疗)。采用肺癌治疗功能评价表(FACT-L量表)分别对身体状况、社会家庭状况、与医生关系、情绪状况、功能状况和附加的关注状况等6个板块进行调查分析。结果社会家庭状况、与医生关系两板块各疗程结束后与治疗前比较差异无显著性(P>0·05),身体状况板块的改善以中医组最优(P<0·05),而情绪板块、功能板块的改善均以中西医组最优(P<0·05)。结论中医药对于化疗的毒副反应有一定的拮抗作用,在一定程度上维护了患者的生存质量。 |
| 英文摘要: |
| ObjectiveTo observe the effect of traditional Chinese medicine (TCM) in improving quality of life of patients with non-small cell lung cancer (NSCLC) in Ⅲ or Ⅳ stage, for establishing TCM therapeutic regimen on late NSCLC. MethodsA total of 294 patients in 6 hospitals were randomly assigned into three groups, 99 in the TCM group treated with TCM according to disease and syndrome differentiation, 92 treated with chemotherapy in the western group and 103 treated with combined therapy of TCM and chemotherapy in the integrative group. Six items, including physical status, social/family status, intercourse with physicians, emotional status, functional status and additional concerning status, were investigated and analyzed by using Functional Assessment of Cancer Therapy-lung (FACT-L). ResultsThe scores of social/family status and intercourse with physicians were insignificantly different in all three groups before and after treatment (P>0.05). The improvement of physical status in the TCM group, and that of emotional status, functional status and additional concerned status in the integrative medicine group were superior to those in the other groups (P<0.05). ConclusionTCM has certain antagonistic effect on the adverse reaction of chemotherapy, and it can improve the quality of life of patients to certain extent. |
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