| 曾娟,左秀丽,魏玮,赵彤,卢雪峰,李延青.荆花胃康胶丸治疗慢性浅表性胃炎临床研究[J].,2006,(6):517-520 |
| 荆花胃康胶丸治疗慢性浅表性胃炎临床研究 |
| Clinical Study on Treatment of Chronic Superficial Gastritis with Jinghua Weikang Capsule |
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| DOI： |
| 中文关键词: 荆花胃康胶丸 慢性胃炎 消化不良 |
| 英文关键词:Jinghua Weikang Capsule chronic gastritis dyspepsia |
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| 中文摘要: |
| 目的观察荆花胃康胶丸治疗慢性胃炎临床疗效。方法慢性胃炎患者90例,随机分为3组:荆花胃康胶丸大剂量组和小剂量组分别用荆花胃康胶丸160 mg和80 mg,每天3次口服;对照组采用吗丁啉10 mg,每天3次口服;疗程均为14天。观察3组消化不良症状积分、胃排空率及生活质量。结果治疗后消化不良症状总积分(分)大剂量组(19．97±1．85)和小剂量组(24．40±1．85)均较治疗前(大小剂量组分别为28．33±1．88、27．70±1．68)降低(P<0．05);3组生活质量均得到明显改善。荆花胃康胶丸不良反应轻微。结论荆花胃康胶丸治疗消化不良症状具有良好的临床疗效和安全性,其中大剂量组疗效优于小剂量组。 |
| 英文摘要: |
| Objective To observe the clinical efficacy and safety of Jinghua Weikang Capsule (JWC) on chronic gastritis (CG). Methods Ninety patients with CG were randomly divided into 3 groups: the control group treated with domperidone 10 mg, 3 times per day orally, the high and low-dose JWC groups treated with JWC 160 mg and 80 mg respectively 3 times per day. The therapeutic course for all groups was 14 days. Dyspeptic symptom score, gastric emptying rate and quality of life (QOL) in patients were observed. Results Dyspeptic symptom score was 19.97±1.85 and 24.40±1.85 after treatment in high and low-dose JWC groups respectively, lower than that before treatment (28.33±1.88 and 27.70±1.68, P<0.05); QOL improved obviously in all the three groups, among which the high-dose JWC group showed the best effect. The adverse reaction of JWC was very mild. Conclusion JWC is an effective and safe drug for alleviating dyspeptic symptoms in patients with CG, its effect is more evident when high dose is applied. |
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