| 金翠香,杨静,孙海峰,王琦.丹参注射液与生脉注射液治疗慢性乙型肝炎的临床对比研究[J].,2006,(10):936-938 |
| 丹参注射液与生脉注射液治疗慢性乙型肝炎的临床对比研究 |
| Comparative Study of the Clinical Effects of Salvia Miltiorrhiza Injection and Shengmai Injection on Chronic Hepatitis B |
| |
| DOI： |
| 中文关键词: 慢性乙型肝炎 肝纤维化 丹参注射液 生脉注射液 |
| 英文关键词:chronic hepatitis B liver fibrosis Salvia Miltiorrhiza Injection Shengmai Injection |
| 基金项目: |
|
| Hits: 1469 |
| Download times: 2 |
| 中文摘要: |
| 目的观察慢性乙型肝炎患者应用丹参注射液和生脉注射液治疗后肝功能和肝纤维化指标的改善情况。方法慢性乙型肝炎患者79例,随机分为丹参组47例,生脉组32例,在常规保肝治疗基础上,两组分别加用丹参注射液和生脉注射液治疗,疗程均为35天。治疗前后观察患者的主要症状、体征及肝功能和肝纤维化指标〔血清透明质酸酶(HA)、层粘连蛋白(LN)、Ⅲ型前胶原(PC-Ⅲ)、Ⅳ型胶原(Ⅳ-C)〕的变化。结果治疗后丹参和生脉均可明显改善慢性乙型肝炎患者症状、体征和肝功能,生脉组较丹参组为优(P<0.05)。治疗后丹参组肝纤维化4项指标较治疗前均有下降(P<0.05);生脉组肝纤维化4项指标与治疗前比较差异无显著性(P>0.05);两组治疗后肝纤维化4项指标比较,差异有显著性(P<0.05)。结论丹参注射液具有改善肝功能和抗肝纤维化功效,生脉注射液虽无抗肝纤维化的作用,但其改善肝功能的疗效较丹参注射液好。 |
| 英文摘要: |
| Objective To observe the effect of Salvia miltiorrhiza Injection(SMI)and Shengmai Injection(SI)on liver function and fibrosis related indexes in patients with chronic hepatitis B.Methods Seventy-nine chronic hepatitis B patients were randomly divided into the SMI group(n=47)and the SI group(n=32),they were treated with SMI and SI respectively on the basis of conventional treatment.The therapeutic course was 35 days for both groups.The changes of main symptoms and physical signs were observed,and indexes of liver function and fibrosis including serum hyaluronidase,laminin,Ⅲ type precollagen(PC-Ⅲ)and Ⅳ type collagen(Ⅳ-C)were investigated before and after treatment.[WT5HZ]Results Symptoms,physical signs and liver functions were improved obviously in both SMI and SI groups,SI showed better effect than SMI(P<0.05).The four liver fibrosis indexes declined significantly in the SMI group after treatment(P<0.05),but no obvious change of those was found in the SI group(P>0.05),showing significant difference between the two groups(P<0.05).Conclusion SMI is effective in improving liver function and inhibiting liver fibrosis,and SI has even better effect in improving liver function than SMI,though it shows no anti-liver fibrosis effect. |
| View Full Text View/Add Comment Download reader |
|
|
|
