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Author Name	Affiliation
WANG Xin	中国中医科学院西苑医院血液科 (北京100091)
MA Rou	中国中医科学院西苑医院血液科 (北京100091)

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中文摘要:

人参药理研究发现其含有皂苷、糖类等多种成分,主要成分为人参皂苷,目前已知40余种人参皂苷单体成分。临床常用来治疗血虚证,但其作用机制并不明确。现就人参皂苷及其组分对正常造血影响的基础研究及临床应用作一综述,发现其对造血细胞、造血微环境及造血调控因子均有作用,提示其对血细胞减少的预防、放化疗保护甚至造血干细胞移植均有潜在的应用价值。

英文摘要:

Ginseng contains multiple components,such as saponins and saccharide,etc.The major is ginsenoside,which includes more than 40 kinds of monomers.It has been applied to treat blood-deficiency syndrome,but the action mechanism is still unclear.The fundamental researches on the effect of ginseng and its components on hematopoiesis and their clinical application were reviewed in this article.They were found to have effects on hematopoietic cells,microenvironment and regulatory factors,indicating they are potential for prevention of hemocytopenia,protection from injury of radiotherapy/chemotherapy and even for transplantation of hematopoietic stem cell.

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