| 傅南琳,孔昭遐.中西药治疗过敏性紫癜肾炎的临床观察[J].,2007,(8):739-742 |
| 中西药治疗过敏性紫癜肾炎的临床观察 |
| Clinical Observation on Treatment of Anaphylactic Purpura Nephritis by Traditional Chinese Herbs and Western Medicine |
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| DOI： |
| 中文关键词: 过敏性紫癜肾炎 中药治疗 西药治疗 激素 |
| 英文关键词:anaphylactic purpura nephritis Chinese traditional herbal therapy Western drug therapy hormone |
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| 中文摘要: |
| 目的比较中药、中药加一般西药和不同剂量激素治疗过敏性紫癜肾炎的疗效。方法对232例过敏性紫癜肾炎的临床资料进行整理和分析。将患者分为单纯中药组、改用中药组、对照Ⅰ组和对照Ⅱ组。单纯中药组和改用中药组予中药治疗;对照Ⅰ组予中药加一般西药加小剂量泼尼松治疗;对照Ⅱ组予中药加一般西药加大剂量泼尼松治疗。观察各组对症状、体征、尿常规、血肌酐尿素氮的综合疗效、疗程和远期疗效。结果4组的综合疗效相近(P>0.05),单纯中药组和对照Ⅰ组的疗程较其他两组短,差异有显著性(P<0.01),各组在相近时间内随访,复发率相似(P>0.05)。结论中药治疗过敏性紫癜肾炎的疗效确切,而且疗程短;单用中药或结合一般西药和小剂量激素是治疗过敏性紫癜肾炎的较好方案,病愈后仍需随访。 |
| 英文摘要: |
| Objective To compare the clinical efficacy of Chinese traditional herbs (CTH) alone or combined with Western medicine (conventional treatment plus different doses of prednisone) in treating anaphylactic purpura nephritis (APN). Methods Clinical data of 232 patients with APN were collected and analyzed. They were assigned to four groups. Patients in Group A1 were treated with CTH; in Group A2 were treated initially with Western medicine but turned midway to CTH; in Group B1 and B2 treated with CTH combined with conventional Western medicine and plus low or high dose of prednisone respectively. The comprehensive clinical efficacy on symptoms,physical signs, routine urine examination, blood creatinine and urea nitrogen, as well as the treatment duration and long-term effect in the four groups were observed. Results There was no significant difference in the comprehensive clinical effects among the four groups (P>0.05). However, the treatment duration was significantly shorter in Group A1 and B1 than in the other two groups (P<0.01). Follow-up study on patients in similar duration showed similar reoccurrence rate among groups (P>0.05). Conclusion Chinese herbs has definite effects on APN with the treatment course shorter than that of other treatments, the optimal protocol for treatment of APN is applying Chinese herbs alone or combined with conventional Western medicine plus low dose prednisone. It is necessary to conduct a follow-up study even though the patients have been cured. |
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