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李小平,郑春盛,洪哲晶,衡先培,胡曼卿.多囊卵巢综合征患者性激素和胰岛素水平与中医证型的相关性[J].,2007,(11):996-998
多囊卵巢综合征患者性激素和胰岛素水平与中医证型的相关性
Correlation between Sex Hormone and Insulin and Various TCM Syndrome Types in Patients with Polycystic Ovarian Syndrome
  
DOI:
中文关键词:  多囊卵巢综合征  性激素  胰岛素  中医证型
英文关键词:polycystic ovarian syndrome  sex hormone  insulin  TCM syndrome type
基金项目:福建省教育厅资助课题(No.JB05158)
Author NameAffiliation
LI Xiao-ping 福建中医学院附属人民医院妇科 福州350004 
ZHENG Chun-sheng 福建中医学院附属人民医院妇科 福州350004 
HONG Zhe-jing 福建中医学院附属人民医院妇科 福州350004 
衡先培 福建中医学院附属人民医院妇科 福州350004 
胡曼卿 福建中医学院附属人民医院妇科 福州350004 
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中文摘要:
      目的探讨多囊卵巢综合征(PCOS)患者性激素和胰岛素水平与中医证型的相关性及临床意义。方法120例患者辨证分为肾阴虚型30例、肾阳虚型30例、脾阳虚型30例、肝郁化热型30例,测定各型患者血清睾酮(T)、促卵泡生成素(FSH)、促黄体生成素(LH)、泌乳素(PRL)、雌二醇(E2)、胰岛素(INS)水平。结果(1)T水平:肾阴虚型患者高于其他3型组(P<0.01),其他3证型两两比较差异无统计学意义。(2)血清LH水平和LH/FSH比值:肾阳虚型高于其他3型组(P<0.05),其他3证型两两比较差异无统计学意义。(3)PRL水平:肝郁化热型高于其他3型组(P<0.01),其他3证型两两比较差异无统计学意义。(4)INS水平:脾阳虚型高于其他3型组(P<0.01),其他3证型两两比较差异无统计学意义。结论T水平增高与PCOS肾阴虚证相关;血清LH水平、LH/FSH比值增高与PCOS肾阳虚证相关;PRL水平增高与PCOS肝郁化热证相关;INS水平增高与PCOS脾阳虚证相关。
英文摘要:
      Objective To explore the relationships of sex hormone and insulin with various TCM syndrome types of polycystic ovarian syndrome (PCOS) and their significance. Methods Levels of testosterone (T), follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), estradiol (E2), and insulin (INS) in 120 patients with PCOS were determined respectively, among them, 30 patients were classified by TCM syndrome differentiation as Shen-yin deficiency type (SYiD), 30 as Shen-yang deficiency type (SYaD), 30 as Pi-yang deficiency type (PYD) and 30 as Gan-stagnancy transformed heat type (GSH). Results It was shown that T level in SYiD, serum LH and LH/FSH ratio in SYaD, PRL in GSH and INS in PYD patients were higher as compared with those in patients of other three types (P<0.05 or P<0.01), except for the above-mentioned, the differences in all the paired comparisons of all the indexes between TCM types were insignificant. Conclusion Elevated level of T, LH and LH/FSH ratio, PRL and INS are correlated with the TCM syndrome type of SYiD, SYaD, GSH and PYD in patients with PCOS respectively, and being the clinical characteristics of the corresponding syndromes.
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