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王海燕,鲍修华,戴俊峰,李彦红,张亦文.散结镇痛胶囊治疗促排卵后卵巢囊肿临床观察[J].,2008,(11):1026-1028
散结镇痛胶囊治疗促排卵后卵巢囊肿临床观察
Treatment of Ovarian Cyst after Ovulation-induction with Sanjie Zhentong Capsule
  
DOI:
中文关键词:  散结镇痛胶囊  卵巢囊肿  促排卵
英文关键词:Sanjie Zhentong Capsule  ovarian cyst  ovulation-induction
基金项目:
Author NameAffiliation
WANG Hai-yan 山东省威海市妇女儿童医院生殖中心 
BAO Xiu-hua 山东省威海市妇女儿童医院生殖中心 
DAI Jun-feng 山东省威海市妇女儿童医院口腔科 
李彦红 山东省威海市妇女儿童医院生殖中心 
张亦文 山东省威海市妇女儿童医院生殖中心 
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中文摘要:
      目的观察散结镇痛胶囊治疗促排卵后卵巢囊肿的疗效。方法将58例促排卵后卵巢囊肿患者采用随机数字表法分为治疗组(33例)和对照组(25例),治疗组应用散结镇痛胶囊治疗1个月,对照组采用期待疗法。比较两组治疗前后雌二醇(E2)、黄体生成素(LH)、卵泡刺激素(FSH)及卵巢囊肿变化。随访囊肿完全消失时间及4个月内受孕情况。结果治疗1个月后治疗组和对照组有效(两侧卵巢无>1.0cm液囊且E2<280pmol/L)率为81.8%(27/33)、52.0%(13/25),两组比较差异有统计学意义(P<0.05)。治疗组E2(220.54±96.23)pmol/L明显低于对照组(372.56±330.62)pmol/L(P<0.05)。LH、FSH的变化无统计学意义(P>0.05)。治疗组平均囊肿消失时间为(1.18±0.46)月,短于对照组(1.96±1.34)月(P<0.05)。4个月内治疗组妊娠率为60.6%(20/33),对照组为32.0%(8/25),两组比较差异有统计学意义(P<0.05)。结论散结镇痛胶囊治疗促排卵后卵巢囊肿疗效较好。
英文摘要:
      Objective To observe the efficacy of Sanjie Zhentong Capsule(SJC)in treating ovarian cyst after ovulation-induction.Methods Fifty-eight patients with ovarian cyst were randomly assigned to two groups,33 in the treated group treated with SJC and 25 in the control group treated with temporization for 1 month.Changes of estradiol(E2),luteinizing hormone(LH)and follicle stimulating hormone(FSH)level as well as condition of cyst before and after treatment were observed and compared.And the time for complete disappearance(TCD)of cyst and the pregnant rate within 4 months were followed-up.Results Effective rate(no fluid cyst sized over 1.0 cm could be found in bilateral ovary and E2<280 pmol/L)in the treated group was 81.8%(27/33)and 52.0%(13/25)in the control group,showing significant difference between them(P<0.05).Level of E2 decreased in both groups,but the lowering was more significant in the treated group,after 1 month,it being 220.54±96.23 pmol/L vs 372.56±330.62 pmol/L(P<0.05).The changes of LH and FSH levels were of no statistical significance(P>0.05).TCD in the treated group was 1.18±0.46 months,which was shorter than that in the control group(1.96±1.34 months,P<0.05).The pregnant rate within 4 months in the two groups was 60.6%(20/33)and 32.0%(8/25)respectively,showing significant difference(P<0.05).Conclusion SJC has good efficacy in treating ovarian cyst after ovulation-induction.
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