欢迎访问中国中西医结合杂志！

需要治疗的病例数(number needed to treat,NNT)是近年来国际上用于评价临床疗效的一个简单而有效的指标,它通过对分类变量数据绝对危险度减低这一指标的计算,能够客观评价干预措施的临床疗效。然而,目前国内对于这一指标临床应用的介绍尚未见报道。本文通过已发表的临床研究文献的实例,解释NNT这一指标及其95%可信区间的计算,并通过其相关名词的解释、荟萃分析的方法等方面说明该指标的具体应用。

英文摘要:

Number needed to treat(NNT)is a simple and effective index for clinical therapeutic effect assessment worldwide accepted in recent years.By calculation of absolute risk reduction(ARR)of classified variables,it made the effect estimate reflect objectively the therapeutic effect of an intervention.However,clinical application of this index was introduced rarely in Chinese literature.With the examples from some published clinical reports,the calculation of NNT and its 95%confidence interval were demonstrated in this paper,and its application was illustrated by some relevant terms explanation and Meta-analysis methods introduction.

View Full Text View/Add Comment Download reader