庞斌,魏品康,李勇进,毛竹君.消痰散结方对裸鼠MKN-45人胃癌组织中VEGF-C及其受体VEGFR-3表达的影响[J].,2011,31(2):204-208 |
消痰散结方对裸鼠MKN-45人胃癌组织中VEGF-C及其受体VEGFR-3表达的影响 |
Effect of Xiaotan Sanjie Recipe on Expressions of VEGF-C and VEGFR-3 in Nude Mice with Transplanted Human Gastric Adenocarcinoma Cell MKN-45 |
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DOI: |
中文关键词: 消痰散结方 胃肿瘤 血管内皮生长因子 血管内皮生长因子受体 转移 |
英文关键词:Xiaotan Sanjie Recipe gastric carcinoma vascular endothelial growth factor vascular endothelial growth factor receptor metastasis |
基金项目: |
庞斌 魏品康 李勇进 毛竹君 |
第二军医大学附属长征医院中医科 (上海200003)
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中文摘要: |
目的 观察消痰散结方对裸鼠MKN-45人胃癌组织中血管内皮生长因子C(vascular endothelial growth factor-C,VEGF-C)及血管内皮生长因子受体3(vascular endothelial growth factor receptor-3,VEGFR-3)表达的影响,探讨消痰散结方防治胃癌淋巴转移的作用机制。 |
英文摘要: |
Objective To observe the mechanism of Xiaotan Sanjie Recipe (XSR) in inhibiting lymphatic metastasis of gastric carcinoma by observing its effects on the expressions of vascular endothelial growth factor-C (VEGF-C) and its receptor VEGFR-3 in nude mice with transplanted human gastric adenocarcinoma cell MKN-45. Methods Thirty mice were made into MKN-45 tumor model and randomly divided into three groups treated with saline,5-Fu,and XSR,respectively. Gene and protein expressions of VEGF-C and VEGFR-3 in the t... |
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