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于庆生,余宏亮,潘晋方,王汉明,帅剑锋,张琦.芪黄煎剂对缺血-再灌注大鼠肠黏膜上皮细胞Bcl-2、Bax及Caspase-3、9 mRNA表达的影响[J].,2011,31(2):223-227

芪黄煎剂对缺血-再灌注大鼠肠黏膜上皮细胞Bcl-2、Bax及Caspase-3、9 mRNA表达的影响

Effect of Qihuang Decoction on mRNA Expressions of Bcl-2, Bax, and Caspase-3, 9 in Intestinal Mucosa Epithelium of Ischemia/Reperfusion Injured Rats

DOI：

中文关键词: 芪黄煎剂缺血/再灌注肠黏膜 Bcl-2 Bax Caspase-3、9 mRNA

英文关键词:Qihuang Decoction ischemia/reperfusion intestinal mucosa Bcl-2 Bax Caspase-3 mRNA Caspase-9 mRNA

基金项目:安徽省高校自然科学基金重点项目(No.KJ2008A44ZC)

于庆生余宏亮潘晋方王汉明帅剑锋张琦

1.安徽中医学院第一附属医院普外科(合肥230031)
； 2.安徽中医学院(合肥230038)
;通讯作者：△现在河南省人口和计划生育科学研究院(郑州450002)

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中文摘要:

目的观察中药芪黄煎剂对缺血-再灌注(ischemia-reperfusion, I/R)损伤大鼠肠黏膜上皮细胞凋亡基因Bcl-2、Bax mRNA表达和信号转导分子Caspase-3、9 mRNA表达的影响。

英文摘要:

Objective To observe the effect of Qihuang Decoction (QHD) on mRNA expression of apoptosis genes Bcl-2,Bax,and signal transduction molecules Caspase-3,9 in intestinal mucosa epithelium of ischemia/reperfusion (I/R) injured rats. Methods Forty Wistar rats were randomized equally into 4 groups,the control group,the model group,the glutamine group,and the QHD group. Rats in the latter two groups were gastric infused with glutamine and QHD respectively for 3 days,but saline was infused instead to rats in the co...

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