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路玫,曹大明,赵喜新,李道明,李建伟,金玉晶,秦庆广,高杨.针灸对环磷酰胺所致骨髓抑制小鼠骨髓细胞周期调节蛋白Cyclin D1表达及细胞周期的动态影响[J].,2011,31(2):238-244

针灸对环磷酰胺所致骨髓抑制小鼠骨髓细胞周期调节蛋白Cyclin D1表达及细胞周期的动态影响

Study on Dynamic Effect of Acupuncture on Marrow Cell Cycle Regulatory Protein Cyclin D1 Expression and Cell Cycle in Mice with Cyclophosphamide Induced Myelosuppression

DOI：

中文关键词: 针灸机理研究环磷酰胺骨髓抑制 Cyclin D1 细胞周期

英文关键词:acupuncture and moxibustion mechanism study cyclophosphamide myelosuppression cyclin D1 cell cycle

基金项目:国家自然基金重大计划(No.90709035)

路玫曹大明赵喜新李道明李建伟金玉晶秦庆广高杨

1.河南中医学院海外教育学院 (郑州450008)
；2.河南中医学院第一临床医学院(郑州450003)
；3.河南中医学院针灸推拿学院(郑州450008)
；4.郑州大学医学院(郑州450000)
;

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中文摘要:

目的探讨针灸抗化疗毒副反应，改善骨髓抑制、提高外周血白细胞数量的分子生物学机制。

英文摘要:

Objective To explore the molecular biological mechanism of acupuncture and moxibustion (A&M) in reducing chemotherapy-related toxicity,relieving myelosuppression and increasing peripheral white blood cells (WBC). Methods Two hundred and twenty-four male Kunming mice of clean grade were randomized equally into 4 groups,the blank control group (A),the model group (B),the acupuncture group (C),and the moxibustion group (D). Except those in Group A,mice were duplicated into myelosuppression model with cyclophos...

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