| 杨积武,徐凤芹,辛莉,孙兰军,高蕊,高改地.心络通片治疗冠心病稳定性心绞痛患者的随机对照研究[J].,2011,31(9):1191-1195 |
| 心络通片治疗冠心病稳定性心绞痛患者的随机对照研究 |
| Effects of Xinluotong Tablet on Stable Coronary Heart Disease Angina:A Randomized Controlled Trial |
| |
| DOI： |
| 中文关键词: 心络通片 稳定性心绞痛 气虚血瘀证 |
| 英文关键词:Xinluotong Tablet stable angina qi deficiency blood stasis syndrome |
| 基金项目: |
|
| Hits: 1772 |
| Download times: 3 |
| 中文摘要: |
| 目的观察具有益气活血补肾作用的心络通片治疗冠心病稳定性心绞痛(气虚血瘀证)的有效性及安全性。方法选取冠心病稳定性心绞痛中医辨证为气虚血瘀证患者240例,随机分为治疗组和对照组,每组120例,分别予心络通片(每次4片,每日3次)、养心氏片(每次3片,每日3次)治疗,进行历时4周的双盲治疗期,观察心绞痛疗效、心电图、运动试验、中医证候改善情况及安全性指标。结果疗后治疗组心绞痛总有效率(91.45%)、心电图总有效率(65.81%)优于对照组(分别为84.87%,55.46%),但差异无统计学意义(P>0.05);两组运动试验、中医证候改善比较差异无统计学意义(P>0.05)。治疗期间两组均无不良反应发生。结论心络通片治疗冠心病心绞痛(气虚血瘀证)安全有效。 |
| 英文摘要: |
| Objective To observe the clinical efficacy and safety of Xinluotong Tablet(XLTT,with actions of benefiting qi,activating blood,and supplementing Shen) in treatment of stable coronary heart disease angina patients of qi deficiency and blood stasis syndrome.Methods 240 stable coronary heart disease angina patients of qi deficiency and blood stasis syndrome were randomly assigned to the trial group and the control group,120 in each group.The trial group was treated with XLTT,four tablets each time,three times a day,while the control group was treated with Yangxinshi Tablet(YXST),three tablets each time,three times a day.The double blinded treatment lasted for four weeks.The therapeutic effects on angina,electrocardiogram(ECG),the exercise test,the improvement of Chinese medicine syndromes,and the safety index were observed.Results The trial group was superior to the control group after treatment in aspects of the therapeutic effects on angina(91.45% vs 84.87%) and the ECG(65.81% vs 55.46%),but with no statistical difference(P>0.05).There was no statistical difference in the the exercise test or the improvement of Chinese medicine syndromes(P>0.05).No adverse reaction occurred during the therapeutic course.Conclusion XLTT was safe and effective in treatment of stable coronary heart disease angina patients of qi deficiency blood stasis syndrome. |
| View Full Text View/Add Comment Download reader |
|
|
|
