| 曾雪,刘瓦利,赵婷,赵俊英,瞿幸,徐志莉,田野,崔炳南,吴小红,张晓红,沈冬,丁旭,华华,闫雨荷,王煜明,乔丽,陈弘平.中药面膜综合疗法治疗寻常痤疮的临床研究[J].,2012,32(5):624-627 |
| 中药面膜综合疗法治疗寻常痤疮的临床研究 |
| Effects of Chinese Medical Facial Mask Comprehensive Therapy in Treating Acne Vulgaris |
| |
| DOI： |
| 中文关键词: 中药面膜综合疗法 寻常痤疮 疗效评价 |
| 英文关键词:Chinese medical facial mask comprehensive therapy acne vulgaris curative effect evaluation |
| 基金项目:国家中医药管理局中医药科学技术研究专项(No.2009ZL07) |
|
| Hits: 1917 |
| Download times: 10 |
| 中文摘要: |
| 目的评价中药面膜综合疗法对Ⅰ～Ⅲ度寻常痤疮的临床疗效及安全性。方法将233例(FAS集)Ⅰ～Ⅲ度寻常痤疮患者随机分为面膜组(113例)和西药组(120例),分别采用中药面膜综合疗法和5%过氧化苯甲酰凝胶外用治疗,面膜组每周治疗2次,西药组每晚治疗1次,均连续治疗4周。分别于治疗1、2、4周后观察皮损积分及中医证候积分改善情况,记录不良反应发生率以及受试者对中药面膜综合疗法使用后的评价。结果 233例病例共完成228例(超窗7例,PPS集221例,其中面膜组105例,西药组116例)。治疗4周后,面膜组皮损及中医证候疗效总有效率明显高于对照组(46.9%vs30.0%,70.8%vs55.8%,P<0.05),FAS集与PPS集统计结果一致。治疗4周后,面膜组PPS集皮损积分及中医证候积分低于西药组,差异均有统计学意义(P≤0.05)。治疗2、4周后,两组FAS集与PPS集皮损积分治疗前后差值及中医证候积分治疗前后差值比较,面膜组均明显大于西药组(P<0.05)。面膜组和西药组不良反应发生率分别为1.8%(2/113)、2.5%(3/120),两组比较差异无统计学意义(P>0.05)。结论中药面膜综合疗法治疗Ⅰ～Ⅲ度寻常痤疮安全有效,不良反应发生率低,易于操作及推广。 |
| 英文摘要: |
| Objective To evaluate the clinical effectiveness and safety of Chinese medical facial mask comprehensive therapy in treating acne vulgaris.Methods Totally 233 acne vulgaris patients(FAS set)in Ⅰ-Ⅲ degree were randomly assigned to the facial mask group(113 cases)and the Western medicine group(120 cases).They were respectively treated with external application of Chinese medical facial mask(twice a week)and 5% benzoly peroxide gel(Benzihex,once in the evening).The treatment lasted for four successive weeks.The integrals of lesions and the improvement of Chinese medicine syndrome integrals were observed 1 week,2 weeks and 4 weeks after treatment respectively.The occurrence of adverse reactions was recorded.The subjects’ evaluation on using the Chinese medical facial mask comprehensive therapy was also recorded.Results Totally 228 of the 233 patients completed the therapeutic course(7 cases of overtime,221 cases of PPS set,105 cases in the facial mask group and 116 cases in the Western medicine group).After 4 weeks of treatment,the lesions and the total effective rate of CM symptoms were obviously higher in the facial mask group than in the control group(46.9% vs 30.0%,70.8% vs 55.8%,P<0.05).The statistical results of FAS set and PPS set showed no difference.After 4 weeks of treatment,the integrals of PPS lesions and the CM syndrome integrals in the facial mask group were lower than in the Western medicine group,showing statistical difference(P≤0.05).After 2 weeks and 4 weeks of treatment,the integrals of lesions and the CM syndrome integrals of FAS set and PPS set were all higher in the facial mask group than in the control group(P<0.05).The occurrence of adverse reactions was 1.8%(2/113)in the facial mask group and 2.5%(3/120)in the control group without statistical difference(P>0.05).Conclusions Chinese medical facial mask comprehensive therapy is safe and effective in treating acne vulgaris of Ⅰ-Ⅲ degree.The occurrence of adverse reactions is very low.It is easy to operate and spread. |
| View Full Text View/Add Comment Download reader |
|
|
|
