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荆雪宁,武继彪.中药多糖诱导肿瘤细胞凋亡的研究进展[J].,2012,32(8):1149-1152
中药多糖诱导肿瘤细胞凋亡的研究进展
DOI:
中文关键词
:
诱导细胞凋亡
中药多糖
肿瘤细胞凋亡
抗肿瘤作用
凋亡相关基因
灵芝多糖
线粒体膜电位
多糖研究
活性氧
剂量依赖性
英文关键词
:
基金项目
:
Author Name
Affiliation
荆雪宁
山东中医药高等专科学校西医教学部
武继彪
山东中医药大学基础医学院
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中文摘要
:
多糖,又称多聚糖,是由醛糖或酮糖通过糖苷链连接而成的多聚物,其分子量一般为数万甚至达数百万,广泛存在于植物、动物和微生物等有机体中,是生命活动不可缺少的一类生物高分子物质。到目前为止,已从天然产物中提取出300多种多糖类化合物,其中从中药中获得的水溶性多糖最为重要[1]。研究表明,中药多糖具有免疫调节、抗肿瘤、抗炎、抗病毒等多种药理作用,尤其是抗肿瘤作用成为中药多糖研究的热点。凋亡,即
英文摘要
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