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朴胜华,郭姣,胡竹平.高脂血症住院患者中医证候临床研究[J].,2012,32(10):1322-1325
高脂血症住院患者中医证候临床研究
Clinical Research of Chinese Medicine Syndromes of Hyperlipidemia Inpatients
  
DOI:
中文关键词:  高脂血症  中医证候  临床研究
英文关键词:hyperlipidemia  Chinese medicine syndrome  clinical research
基金项目:国家自然科学基金资助项目(No.30973913);广东省自然科学基金面上项目(No.07003155)
Author NameAffiliation
朴胜华  
郭姣  
胡竹平  
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中文摘要:
      目的通过对高脂血症住院患者的中医证候临床调研,探讨高脂血症中医证型分布规律。方法采用自拟《高脂血症中医证候临床调查表》收集316例高脂血症住院患者的血脂分类、分级,合并症,以及中医症状、舌象、脉象等临床资料,进行统计分析。结果 316例高脂血症患者中医单证辨证以肝气郁证最为多见(66.46%)。肝郁脾虚证(35.44%)、肝肾阴虚证(16.77%)、脾肾阳虚证(13.61%)、痰瘀内阻证(13.29%)、阴虚阳亢证(9.18%)是高脂血症5个常见中医复合证型。肝郁脾虚证在所有类型、程度的高脂血症中均占有最高构成比。对高脂血症的分类研究结果表明,混合型合并低高密度脂蛋白胆固醇(HDL-C)型最多见(108/316,34.18%),其次为混合型高脂血症(81/316,25.63%),总计混合型占59.81%(189/316),高于总胆固醇(TC)增高型(16.77%)和甘油三酯(TG)增高型(23.42%)。结论肝郁脾虚证可能是影响高脂血症脂质代谢的核心证型。高脂血症临床以混合型高脂血症多见,临床用药需兼具降TC、TG和升高HDL-C3种作用。
英文摘要:
      Objective To study the Chinese medicine (CM) syndrome typing of hyperlipidemia inpatients, thus exploring the CM syndrome typing laws. Methods The clinical materials, including blood lipids, grading, complications, CM symptoms, and manifestations of tongue and pulse were recorded using self-formulated epidemiological questionnaire of CM syndrome in hyperlipidemia, and then these materials were statistically analyzed. Results Gan-qi stagnation syndrome (66.46%) was the most often seen syndrome in the 316 hyperlipidemia inpatients. Gan stagnation Pi-deficiency syndrome (35.44%), Gan-Shen yin deficiency syndrome (16.77%), Pi-Shen yang deficiency syndrome (13.61%), inner stagnation of phlegm and stasis syndrome (13.29%), hyperactivity of yang and hypoactivity of yin syndrome (9.18%) were 5 common syndromes of hyperlipidemia. Gan stagnation Pi-deficiency syndrome occupied an important position among all types and at various levels. Results from the lipid classification of hyperlipidemia showed that mixed type with low HDL-C was the most often seen (108/316,34.18%), followed by mixed hyperlipidemia (81/316,25.63%). Totally the mixing type accounted for 59.81% (189/316), higher than hypertriglyceridemia (16.77%) and hypercholesterolemia (23.42%). Conclusions Gan stagnation Pi-deficiency syndrome might be the core syndrome affecting the lipid metabolism of hyperlipidemia. Mixed hyperlipidemia was the most often seen in clinics. Clinical medication should cover actions of decreasing TC and TG, and increasing HDL-C.
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