| 赵浩,王丹.类风湿关节炎伴发抑郁的中医临床证型分布特点[J].,2013,33(09):1208-1211 |
| 类风湿关节炎伴发抑郁的中医临床证型分布特点 |
| Distribution Features of Chinese Medical Syndrome Types of Rheumatoid Arthritis Patients Accompanied with Depressive Symptoms |
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| DOI：10.7661/CJIM.2013.09.1208 |
| 中文关键词: 中医临床证型 抑郁症状 类风湿关节炎 |
| 英文关键词:Chinese medical clinical syndrome type depressive symptom rheumatoid arthritis |
| 基金项目:上海市卫生局中医药科研基金资助项目（No2012QL044A） |
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| 中文摘要: |
| 目的 探讨类风湿关节炎（RA）伴发抑郁症状的中医证型特点。方法 采用抑郁自评量表（SDS）对263例RA患者进行抑郁症状评价，分析抑郁症状与改良疾病活动性标准（DAS28）之间的关系，评价伴发抑郁症状的RA患者中医证型特点。结果 痰瘀痹阻型、气血两虚型中伴有抑郁症状的患者比例分别为47.2%和45.8%，较其他组明显增多，差异有统计学意义（P<0.05）；有抑郁症状的RA患者DAS28评分增高，病程较长，但年龄无明显差异；学历高的RA患者伴有抑郁症状的例数高于学历低者。结论 RA患者的中医证型与抑郁症状存在一定的关系，痰瘀痹阻型和气血两虚型发生的患者例数相对偏高；DAS28评分离、病程长与学历高可能是RA并发抑郁症状的危险因素。 |
| 英文摘要: |
| Objective To explore features of Chinese medical syndrome types in rheumatoid arthritis （RA） patients accompanied depressive symptoms. Methods The degree of depressive symptoms was assessed in 263 RA patients using self rating depression scale （SDS）. The correlation between depressive symptoms and modified Disease Activity Score （DAS28） were analyzed. The features of Chinese medical syndrome types of RA patients accompanied with depressive symptoms were also assessed. Results The percentage of these patients of sputum stasis obstruction syndrome （SSOS） was 47.2% and that of qi blood deficiency syndrome （QBDS） was 45.8%， obvious higher than that of other groups （P<0.05）. DAS28 score was higher and their course of the disease was longer in RA patients accompanied with depressive symptoms. But there was no obvious difference in age. There were more RA patients with depressive symptoms holding higher levels of certificate than those holding lower levels of certificate. Conclusions There was certain correlation between Chinese medical syndrome types and depressive symptoms in RA patients. RA patients of SSOS and QBDS were easier to suffer from depressive symptoms. Higher DAS28， longer course of the disease， and holding higher levels of certificate might be three risk factors for RA patients accompanied with depressive symptoms. |
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