| 李婧;赵珊珊;潘紫萌;孙畅;徐珂;匡洪影.基于膏脂理论和脂代谢重编程探讨多囊卵巢综合征病机[J].,2024,44(1):101-106 |
| 基于膏脂理论和脂代谢重编程探讨多囊卵巢综合征病机 |
| Pathogenesis of Polycystic Ovary Syndrome Based on the Theory of Lipids Theory and Lipid Metabolism Reprogramming |
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| DOI：10.7661/j.cjim.20230930.334 |
| 中文关键词: 多囊卵巢综合征 膏脂理论 脂代谢重编程 脂质代谢 中西医结合 |
| 英文关键词:polycystic ovary syndrome lipids theory lipid metabolism reprogramming lipid metabolism integrative medicine |
| 基金项目:国家自然科学基金资助项目（No.82174422，No.82374509）;2018年黑龙江省博士后科研启动金（No.LBHQ18119）;黑龙江中医药大学校杰出人才基金（No.2018jc05）;中国中西医结合妇产科专项研究基金（No.FCK-ZSYTW-08） |
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| 中文摘要: |
| 多囊卵巢综合征（PCOS）是一种复杂的多因素内分泌代谢紊乱性疾病，病因涉及遗传因素和生活方式的相互作用，其中脂代谢重编程机制可能是PCOS病机中的中心环节。在中医古籍中阐述的相关膏脂理论表明膏脂失衡易诱发肥人不孕。故笔者基于膏脂理论和脂代谢重编程机制，探讨膏脂失衡与脂代谢重编程异常对PCOS的作用与影响，为临床诊疗PCOS提供新思路。 |
| 英文摘要: |
| Polycystic ovary syndrome （PCOS） is a complex multifactorial endocrine and metabolic disorder， which may involve the interactions between genetic factors and lifestyles. The reprogramming mechanism of lipids metabolism might be an important central link in the pathogenesis of PCOS. The theory of lipids described in traditional Chinese medicine classics showed the imbalance of lipids easily induced infertility in the obesity. Therefore， based on the theory of lipids and the reprogramming mechanism of lipid metabolism， authors discussed the roles and effects of lipids imbalance and abnormalities of lipid metabolism reprogramming， thus providing new ideas for clinical diagnosis and treatment of PCOS. |
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