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金敬善,王广才,张绳祖,李伍善,何俊仁,王丽华,危北海.血清中胃泌素水平与脾虚证的关系[J].中国中西医结合杂志,1982,(1):25-26,62
血清中胃泌素水平与脾虚证的关系
The Relation between Serum Gastrin Level and the Syndrome of Deficiency in the Spleen
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DOI:
中文关键词:  血清胃泌素水平  脾虚证  系统功能  正常人  胃分泌功能  四君子汤  动物血清  胃肠道激素  临床观察  胃肠道运动
英文关键词:
基金项目:
作者单位
金敬善 北京市中医研究所 
王广才 北京市中医研究所 
张绳祖 北京市中医研究所 
李伍善 北京市中医研究所 
何俊仁 北京市中医研究所 
王丽华 北京市中医研究所 
危北海 北京市中医研究所 
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中文摘要:
      祖国医学认为"脾为后天之本",主运化、升清降浊、为营血生化之源等,由此看来,中医"脾"的本质可能与消化系统功能有关。我们用血清中胃泌素水平作为胃分泌功能指标,对脾虚证进行了观察。中医辨证标准我们制定的脾虚者的辨证指标为:1.面色苍白少
英文摘要:
      Taking the serum gastrin level as an index,the patients with spleen-deficiency symptoms were observed and compared with the normal. The serum gastrin mean level of 31 normal cases was 130.0±44.0 pg/ml,whereas the level of 14 cases of deficiency patients who had spleen-deficiency symptoms was 73.2±33.7 pg/ml.The latter is significantly lower than the normal(P<0.001).There is no significant difference between other groups of differentiation of symptom-complexes in TCM and the normal(P>0.05). 20 normal mice were observed.Their serum gastrin mean level was 451±74 pg/ml.The corresponding figure for 18 spleen-deficiency mice was 344±68 pg/ml,which is significantly lower than the normal(P<0.05).After the treatment with decoction of four noble ingredients(四君子汤),it seems that there is a rise in the serum gastrin mean level. A preliminary discussion with regard to the above-mentioned results suggests that the decrease of the serum gastrin level might be one of the pathologic mechanisms leading to spleen-deficiency.Clinically,it might serve as an index of observation of the dysfunction of the spleen in transporting and distributing nutrients and water(脾 失健运).
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