中药止泻Ⅰ、Ⅱ号治疗婴幼儿秋季腹泻及其对小肠吸收功能的影响

作者	单位
倪珠英	湖北中医学院附属医院儿科腹泻组
倪群芝	湖北中医学院附属医院儿科腹泻组
朱筱秀	湖北中医学院附属医院实验室

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中文摘要:

对172例婴幼儿秋季腹泻设中、西医两组对照治疗,并观察了中药止泻Ⅰ、Ⅱ号对小肠吸收功能的影响。结果两组有效率虽无明显差别,但中医组在退热、止呕、大便次数及性状的恢复时间等方面较西医组快。大便内糖含量测定及 D-木糖吸收试验也提示中药止泻Ⅰ、Ⅱ号对秋季腹泻患儿小肠绒毛细胞吸收功能恢复有促进作用。

英文摘要:

From 1979 to 1981,172 patients with acute infantile gastroenteritis had been admitted to our hospital in autumn.They were divided randomly into 2 groups:group 1 consisting of 81 patients were treated with traditional Chinese antidiarrheals No.1 and No.2,group 2 composed of 91 patients were treated symptomatically. The therapeutic effects showed no significant difference between the 2 groups.But the average duration of fever,vomiting and diarrhoea of group 1 was significantly shorter than that of group 2.The number of days of total course of disease in patients who receivcd treatment in the early stage(within 3 days after onset)of group 1 and group 2 were 5±0.429 and 6.5±0.473 respectively,showing significant difference. The intestinal sugar secretion of group 1 after treatment was 0.574±0.308mg/g,much lower than the level of group 2 which was 4.473±1.038mg/g and much lower than that in normal infants which was 2.315±0.629mg/g. The mean concentration of D-xylose absorption of the 2 groups before treatment was 167.548±14.857μm/dl. It increased to 255.636±32.59μm/dl in group 1 after treatment,an increase much greater than that of the control group. This study suggests that antidiarrheals No.1 and No.2 are effective for curing acute infantile gastroenteritis. Probably these traditional Chinese drugs have the action of improving the absorption of the small intestine,so the course of disease was shortened when they were used at an earlier stage of disease.

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