芪甲丹注射液对丙线照射家兔微循环障碍的改善作用

Effects of Qi Jia Dan Injection(芪甲丹注射液)on Improving Microcirculatory Disturbances of Rabbits Irradiated with γ-rays—Determination of Blood Circulation Time and Capillary Permeability by Fluorescence Angiography

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中文关键词: 毛细血管通透性微循环障碍注射液循环时间家兔改善作用照射微血管造影球结膜微循环放射损伤

英文关键词:

基金项目:

作者	单位
王洪复	上海第一医学院工业卫生研究所
陈永明	上海第一医学院工业卫生研究所
袁龙宝	上海第一医学院工业卫生研究所
励杏娣	上海第一医学院工业卫生研究所
钟锦秀	上海第一医学院工业卫生研究所

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中文摘要:

本文报道应用荧光微血管造影法测定丙线照射家兔的耳—眼循环时间和球结膜毛细血管通透性,显示400拉德照射兔的耳—眼循环时间明显延长,毛细血管通透性增高。经芪甲丹注射液治疗,上述指标减轻,表明该注射液可促进放射损伤的修复。

英文摘要:

The blood circulation time from ear to eye determined by fluorescence angiography of bulbar conjunctival microvessels of rabbits may be taken as an index of blood velocity in the laboratory.It may also be used to observe the capillary permeability.This paper reports that the ear to eye blood circulation time of normal rabbits was found to be 6.20±0.94 sec,and the circulation time of rabbits irradiated with 400 rads of γ-rays was prolonged,especially on the 7th and 11-12th day which was tbund to be 7.92±1.89 see and 8.27±1.59 sec respectively.The capillary permeability also increased markedly after irradiation.The blood circulation time of rabbits given Qi Jia Dan injection(芪甲丹注射液)after irradiation returned to normal.The capillary permeability was also mitigated.Morphologic changes were found improving.

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