复方中药为主治疗亚急性重型肝炎临床及实验观察

作者	单位
王国申	上海市传染病医院
李家琦	上海市传染病医院
巫善明	上海市传染病医院
陈光铎	上海市传染病医院
施明	上海市传染病医院

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中文摘要:

本文采用复方中药为主的中西医结合方法治疗亚急性重型肝炎169例,死亡119例;在病情相仿的情况下,同期还用单纯西药治疗46例作为对照,死亡41例。两组病死率分别为70.4%、89.1%,差异显著(P<0.05),有统计学意义。中药应用茵栀黄注射液和大黄复方汤剂,经实验观察到,茵栀黄和大黄具有辅助诱生干扰素的作用。

英文摘要:

In the period of 1972-1983,169 patients with subacute severe hepatitis were treated mainly with Yin Zhi Huang injection(茵栀黄注射液,YZHI)and rhubarb decoction(RD)combined with western medicines(group A),while other 46 patients(group B)with the same conditions treated with western medicines only were randomized as control.The death rates of these two groups were 70.4% and 89.1% respectively.There were significant difference between them(P<0.05). According to the laboratory observation YZHI and 10% RD had its ability to induce interferon and the serum level of the latter was elevated twice more than normal.The frequencies of the complications with infections in these two groups treated with corticosteroid were 50% and 70% respectively.The survival rates of each group after this were 24.5% and 7.7% respectively.However,there were no significant differences between them(P>0.05)but it demonstrated that group B showed poorer ability to prevent infection and less effect of controlling the infection than group A.It is held that the therapeutic effect of group A is better than that of group B.Thus,it reveals that in this observation the treatment of the traditional medicines combined with western medicines is better than that of western medicines alone.

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