胃肠复元汤在腹部术后应用的临床疗效观察和实验研究

作者	单位
马必生	北京积水潭医院
陈婉珠	北京积水潭医院
裴德恺	大连医学院
李永渝	大连医学院
高静涛	大连医学院
邢嵘	大连医学院
仲玉山	空军大连医院
王光瑞	空军大连医院
毕庚年	河北医学院三院
李乐天	河北医学院三院
杨相风	河北医学院三院
杨熙平	黑龙江省医院

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中文摘要:

本文介绍胃肠复元汤应用于腹部手术防治术后胃肠功能紊乱和肠麻痹的临床疗效观察和实验研究。通过对腹部术后406例进行前瞻性随机对照临床疗效观察,部分病例应用肠音描记仪进行直接肠音图象描记,证实给药组具有非常明显的早期促进胃肠功能恢复的作用。同时在对 Wistar 大白鼠进行腹部手术模型的多指标对照观察中,证实了胃肠复元汤在促进术后胃肠的早期运动功能和消化吸收功能,以及在增加胃肠血流供应等方面,均具有良好的作用。

英文摘要:

A prospective clinical study was carried on 406 patients after abdominal operation.The treated group(203 cases)were administered randomly with the electuary of Wei Chang Fu Yuan Tang(to recover gastrointestinal function)supplied by the drugstore"Tong Ren Tang"(同仁堂)in Beijing.Each patient took a dosage of 25～50 gm diluted with water given orally or infused through the nasogastric tube 2～4 times a day for about 3 days.The other 203 cases received the same routine treatment and a dosage of saline as control.The main kinds of operation included subtotal gastrectomy,intestine resection and biliary operation.The purpose of the study was to observe the effects of the electuary on the recovery of gastrointestinal dysfunction during postoperation period.It was demonstrated that the presentation of bowel sounds,flatus and bowel wind were significantly,earlier in the treated group than the control.The duration of therapeutic process of gastric aspiration and intravenous infusion was shorter too.About half of the patients in the treated group did not take any gastric aspiration.In this study,40 cases were measured with intestinophonography.It seemed that the frequency and amplitude of bowel sounds were both high in the treated group.Differences in the recovery of intestinal activity between the two groups were significant statistically.According to a series of experimental studies performed in SD rate. It has been shown that the decoction of Wei Chang Fu Yuan Tang has marvelous recovering effect on various gastrointestinal functions,such as the emptying motility of stomach;the propulsion action of small intestine;the action potential and frequency of spike burst generation in the stomach and duodenum;the secretion of pancreatic amylase;the absorption of water and glucose in the small intestine;and the blood flow in the portal vein,mesenteric circulation and gastroduodenum tissues.All of them were in the portal vein,mesenteric circultaion and gastroduodenum tissues.All of them were enhanced by the decoction infusion.This suggests that Wei Chang Fu Yuan Tang not only has an effect on the motility,but also on the secretion,absorption and blood supply of gastrointestine.

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