| 黄跃兰.天花粉治疗19例恶性滋养叶肿瘤的临床观察[J].中国中西医结合杂志,1987,(3):154-155,132 |
| 天花粉治疗19例恶性滋养叶肿瘤的临床观察 |
| A Clinical Study on Treatment of Malignant Trophoblastic Neoplasia with Trichosanthin |
| 免费下载全文 查看/发表评论 下载PDF阅读器 |
| |
| DOI： |
| 中文关键词: 天花粉素 滋养叶 叶细胞 恶性肿瘤 临床观察 手术治疗 免疫功能 绒癌 直接作用 引产 |
| 英文关键词: |
| 基金项目: |
|
| 摘要点击次数: 1257 |
| 全文下载次数: 837 |
| 中文摘要: |
| 本文报告了用中药天花粉加手术治疗恶性滋养叶肿瘤19例,除2例Ⅱ、Ⅲ期绒癌并恶病质死亡外,17例得以根治。通过临床观察及实验室验证,天花粉可直接作用于绒毛滋养叶细胞,使之变性坏死,并可提高机体的免疫功能。提示天花粉可作为治疗恶性滋养叶肿瘤的选用药物之一。 |
| 英文摘要: |
| Malignant trophoblastic neoplasia is a common but highly malignant tumor.Affirmative effect has been obtained through chemotherapy.The major problems are serious side effects,long course of treatment and high cost.In 5,000 induced abortion patients with trichosanthin(TCS),their histological degeneration and necrosis of villi has been observed,so TCS has been used for treating choriocarcinoma and invasive mole since 1970.From 1970 to 1978,19 cases of choriocarcinoma and invasive mote were treated with TCS alone. 17 of them survived without additional treatment and recurrence after 8～16 years follow-up,the remaining 2 cases died of severe choriocarcinoma.It is speculated that the main pharmacological mechanism of TCS is its direct action on trophoblastic tissue and stimulates the immune function of organisms in controlling choriocarcinoma and invasive mole.TCS originated in China.It is characterized by rich resources,low cost. short treatment course and relatively mild side-effect,it may enhance the effect of chemotherapy and therefore TCS is recommended among the agents in treating malignant trophoblastic neoplasia. |
| 关闭 |
|
|
|
扫描微信二维码，获取更多信息