颅痛宁煎剂治疗血管性头痛的临床及实验研究

用颅痛宁煎剂及复方羊角冲剂分组治疗350例血管性头痛患者,并作对比观察。颅痛宁组300例,治愈226例(75.3%),好转63例(21.0%),总有效率96.35;复方羊角冲剂组50例,治愈28例(56.0%),好转13例(26.0%),总有效率82.0%。颅痛宁组疗效明显高于复方羊角冲剂组(P<0.01)。实验研究也初步证明,颅痛宁有明显的镇痛作用。

英文摘要:

Observing the therapeutic effect of 350 cases of vascular headache patients treated with oral Lutongning decoction and goat horn compound separately,and comparing the effects of these two groups’patients,they showed that the former yeas much better than the latter.The author found that cure rates of these two groups were 75.3% and 56% respectively(P<0.01).The medicinal action of the former was also faster than that of the latter,and the time to recover was shorter.So, Lutongning was an effective prescription in the treatment of vascular headache.In order to research the effective mechanism of Lutongning on vascular headache,the animal experiment was carried out.The hot-plate method and acetic acid body-turning method were used for the experiment in rats. After perfusing Lutongning into the rat’s stomach,the author found that the reaction times by hot-plate method and the turning times by acetic acid body-turning method were less than those of the control animals.The result showed that the analgetic effect of this decoction was more obvious.

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