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李安国,贺石林,邓常青,彭延古.补阳还五汤对血管壁抗血栓功能的影响[J].中国中西医结合杂志,1989,(9):545-547,517
补阳还五汤对血管壁抗血栓功能的影响
Studies of the Effests of Buyang Huanwu Decoction on the Antithrombotic Functions of Vessel Wall
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DOI:
中文关键词:  补阳还五汤  抗凝血酶  灌流液  血管壁  纤维蛋白原  人脐静脉  抑制活性  抗血栓  蛋白质  因子
英文关键词:
基金项目:国家自然科学基金资助课题
作者单位
李安国 湖南中医学院活血化瘀研究室 
贺石林 湖南医科大学 
邓常青 湖南中医学院活血化瘀研究室 
彭延古 湖南中医学院活血化瘀研究室 
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中文摘要:
      用人脐静脉灌流方法研究了补阳还五汤对血管壁抗血栓特性的影响,结果表明,补阳还五汤具有抑刺凝血酶刺激血管壁释放 vW 因子的作用,并抑制凝血酶凝固纤维蛋白原的活性,但不影响血管壁对凝血酶的吸附。实验未观察到补阳还五汤对凝血酶刺激血管壁释放前列环素和纤溶抑制活性的作用有何明显影响。
英文摘要:
      The effects of Buyang Huanwu Decoction(BYHWD)on the antithrombotic functions of vessel wall were studied with human umbilical.vein perfusion.It was observed that the both of Von Willebrand factor release stimulated by thrombin from the vessel walls and conversion of fibrinogen to fibrin catalyzed by thrombin were inbibited by BYHWD.There were no obvious effects of BYHWD on the thrombin adsorption to the vessel walls and the thrombin induced release of PGI, as well as fibrinolysis inhibiting activity from the vessel walls.
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