54例冠心病血脂15年动态观察及与中医辨证、治疗相关研究

作者	单位
鲍军	浙江医科大学附属第二医院中医研究室
楼建国	浙江医科大学附属第二医院中医研究室
洪允祥	浙江医科大学附属第二医院中医研究室
詹小萍	浙江医科大学附属第二医院中医研究室
张华	浙江医科大学附属第二医院中医研究室
李灵	浙江医科大学附属第二医院中医研究室

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中文摘要:

54例冠心病患者胆固醇增高率为33.33%。将本组分为胆固醇正常(Ⅰ)与增高(Ⅱ)组,通过15年观察:Ⅰ组胆固醇基本保持正常水平,甘油三酯仅略高于正常;而Ⅱ组虽经正规降脂药物治疗,但胆固醇及甘油三酯仍明显增高;与Ⅰ组比 P<0.05。与中医辨证联系,无论胆固醇、甘油三酯均以阳虚和阴阳两虚型为高,尤以甘油三酯明显(P<0.01)。甘油三酯以血瘀型为高(P<0.01)。两组除降脂药物外,均应用相同的中西医结合治疗。而15年的远期疗效,则Ⅰ组明显高于Ⅱ组,提示血脂增高的冠心病,治疗难度较大。

英文摘要:

The increasing rate of Cholesterol(CH)of 54 cases w-ith coronary heart disease was 33.33%. According to CH level,the authors divided them into two groups:the normal one(Ⅰ)and the high one (Ⅱ).By fifteen-year observation,CH of Group Ⅰ kept normal,only with its triglyceride(TG)a little higher than ordinary level.But the CH and TG of Group Ⅱ,which had been treated with anticholes- teremic drugs,was obviously higher than Group Ⅰ(P<0.05).In connection with identification according to TCM,both CH and TG of deficiency of Yang(阳),and deficiency of both Yin(阴)and Yang were higher,especially TG(P<0.01).TG of the type of blood stasis was higher(P<0.01)except anticholesteremic drugs for Group Ⅱ.The two groups were treated with the same combined treatment of TCM and WM.The long term effect of fifteen years in Group Ⅰ was more obvious than in Group Ⅱ.This showed that the treatment of high serum lipid of CHD was more difficult.

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