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叶毓奇,王秀云,钟有志.矽复康治疗矽肺53例疗效观察[J].中国中西医结合杂志,1990,(7):420-421,389
矽复康治疗矽肺53例疗效观察
Clinical Therapeutic Effect of Xifukang(矽复康)on 53 Patients with Silicosis
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DOI:
中文关键词:  矽复康  莨菪类药  矽肺  微循环  活血化瘀
英文关键词:
基金项目:
作者单位
叶毓奇 江西弋阳蛇纹石矿职工医院 
王秀云 江西弋阳蛇纹石矿职工医院 
钟有志 江西上饶地卫生区防疫站 
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中文摘要:
      矽复康是以莨菪类药为主的中药复方制剂,具有活血化瘀、疏通微循环、提高免疫功能、增强肺的廓清能力等作用,经3年来53例临床观察,对改善矽肺患者的临床症状,恢复肺功能,增强患者体质,恢复劳动力等均有较明显的效果。部分原有胸闷,气急,行走或上楼都感困难者,经治疗后都有不同程度的恢复,有的已恢复原工作。
英文摘要:
      Xifukang is a compound preparation of Chinese herbs consisting of Hanbane grugs mainly.Since 1987,the significant effeciency have been obtained in treatment of 53 patients suffering from silicosis by self-control study.The results indicated that the clinical manifestations including dyspnea,cougn, sputum production,chest pain,weakness,etc.were markedly improved(P<0.01)and measurements of pulmonary function(FVC,FEV and MVV)significant enhanced(P<0.01).After treatment 20 cases roentgenogram exam showed that the lung’s clarity and the limited emphysema were im- proved,the silicolic nodule and mass-mergence opacity of 3 cases lessened in some degree.By discussing the effect of Xifukang which might lower the collagen protein content of experimental silicosis of Wistar rats and improve pathomorphous.The authors concluded that the therapeutic mechanism of Xifukang could be the actions of this remedy on promoting blood circulation to eliminate blood stasis dredging microcirculation,increasing ventilation/perfusion-(V_A/Q),protecting dust-cells,resisting fibrosis,regulating immune function,enhancing lung clearance,postponing and preventing.development of silicosis.
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