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马秋晖,居云龙,张兆麟,陆文涛,董建国,高蓉.心身灵治疗虚证型精神分裂症临床免疫学观察[J].中国中西医结合杂志,1991,(4):215-217,197
心身灵治疗虚证型精神分裂症临床免疫学观察
The Immunological Study of Inefficiency Schizophrenics with Deficiency Syndrome Treated with Xin Shen Ling(心身灵)
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DOI:
中文关键词:  心身灵  虚证型精神分裂症  免疫测定
英文关键词:Xin Shen Ling  inefficiency schizophrenics  deficiency syndrome immunology
基金项目:
作者单位
马秋晖 苏州市广济医院中西医结合研究组 
居云龙 苏州市广济医院中西医结合研究组 
张兆麟 苏州市广济医院遗传免疫学研究组 
陆文涛 苏州市广济医院遗传免疫学研究组 
董建国 苏州市广济医院遗传免疫学研究组 
高蓉 苏州市广济医院遗传免疫学研究组 
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中文摘要:
      本文对30例虚证型精神分裂症进行了 T、B 淋巴细胞、裸细胞(N)、双标记细胞(D)、大颗粒淋巴细胞(LGL)、免疫复合物(CIC)、植物血凝素(PHA)皮试七项免疫指标的测定并与30例正常健康人对照比较。结果发现除 LGL 细胞外,六项免疫指标患者组与对照组之间均有着显著性差异,P<0.01。应用中药免疫调节剂"心身灵"进行治疗,结果 T、N、D 细胞和 CIC,PHA 皮试五项免疫指标与疗前对比均具显著性差异,P<0.01。与对照组相比则无明显差异。
英文摘要:
      This paper reports 30 cases of chronic schizophrenics with deficiency syndrome who had chronically taken many sorts of neuroleptic medications and other therapies to be ineffective.The 7 immunological functioning markers were detected:phytohemagglutinin(PHA)intradermic test; circulating.immune complex(CIC);T,B lymphocytes,null(N),double(D)cell;and large granular lymphocyte(LGL)and to be compared with a control group of 30 healthy individual.The result showed that 6 immunological markers(PHA,CIC and T,B,N and D cell)were significantly different as compared with the control group(P<0.01).In order to regulate proportion and function to immune cell,the 30 patients were given to take immuno-modulating herbs(Xin Shen Ling,XSL) during 6 weeks,while their 7 immunological markers were detected before treatment(BT)and after treatment(AT).The results showed that 5 immunological markers(PHA,CIC.T,N.and D cell)of BT were significantly different as compared with that of AT(P<0.01).However,the 5 im- munological markers(PHA,CIC.and T,N and D cell)of AT were not significantly different as compared with that of the control group(P>0.05).The brief psychosis rating scaie(BPRS)and nurses observation scale for inpatient evaluation(NOSIE)were used as evaluating changes of clinical symptoms BT and AT.The results showed that BPRS and NOSIE of BT were significantly different as compared with that of AT(P<0.05).The clinical efficacious rate was 67%.We have followed up the results for near 3 years which had a relapse of 5 cases of 20 cases be discharged.It seemed that XSL may be one of the preventive relapse agent for these patients.
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