外伤性视神经萎缩的血液流变学改变

本研究通过对外伤性视神经萎缩患者与健康对照的血液流变学比较,发现外伤性视神经萎缩发病除单项红细胞压积无差异外,其余5项指标均呈显著差异(P<0.01)。同时通过对此类患者的治疗前后血流变学的检查,结果表明中药对外伤性视神经萎缩患者中的红细胞沉降率、纤维蛋白原两项指标改善有意义(P<0.01)。作者认为出现这一血液流变性的改变是由于外伤后引起微循环障碍,即在微循环血流中,出现血红细胞聚集程度的增加,红细胞内粘度与刚性的升高,而它们所造成的影响均可通过"逆转现象"而被放大对血液流动的阻力,从而使其血流变性引起变化。

英文摘要:

Guang An Men Hospital.China Academy of Traditional Chinese Medicine.Beijing(100053) Whole blood viscosity (WBV),plasma viscosity (PV),hematocrit,erythrocyte sedimentation rate (ESR)and fibrinogen were assayed in 20 patients with traumatic optic nerve atrophy.The results of each item in the above examinations has been compared with that of the control group.It has been demonstrated that WBV.PV,ESR and fibrinogen in the patient group were significantly higher than that in the control group(P<0.01).But the ESR and fibrinogen of the treatment group were significantly lower than that in the pretreatment group (P<0.01).The authors suggest that the result of changes in hemorheology of traumatic optic nerve atrophy is a kind of reverse phenomenon.

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